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Selected Publications

10-Glaucoma-publications

Showing 1 - 10 out of 10

01

Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi:10.1167/iovs.17-22531.
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O'Brien CJ.

02

Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi:10.1167/iovs.17-22400.
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O'Brien CJ.

03

Aging and ocular tissue stiffness in glaucoma.

Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O'Brien CJ.

04

The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.

Exp Eye Res. 2016 Jan;142:102-9.
Wallace DM, O'Brien CJ.

05

Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cell’.

Br J Ophthalmol.2015 Mar 20.pii: bjophthalmol-2014-306093.
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O'Brien CJ.

06

The role of matricellular proteins in glaucoma.

Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4.
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ.

07

Anticonnective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.

Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .

08

The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
Quill B, Docherty N, Clark AF, O'Brien CJ.

09

Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.

Mol Vis. 2011;17:1182-91.
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O'Brien CJ, Wallace DM

10

Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucoma

Kirwan RP, Wordinger RJ, Clark AF, O'Brien CJ.

Showing 1 - 10 out of 10

10

Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucoma

Kirwan RP, Wordinger RJ, Clark AF, O'Brien CJ.

09

Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.

Mol Vis. 2011;17:1182-91.
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O'Brien CJ, Wallace DM

08

The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
Quill B, Docherty N, Clark AF, O'Brien CJ.

07

Anticonnective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.

Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .

06

The role of matricellular proteins in glaucoma.

Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4.
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ.

05

Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cell’.

Br J Ophthalmol.2015 Mar 20.pii: bjophthalmol-2014-306093.
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O'Brien CJ.

04

The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.

Exp Eye Res. 2016 Jan;142:102-9.
Wallace DM, O'Brien CJ.

03

Aging and ocular tissue stiffness in glaucoma.

Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O'Brien CJ.

02

Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi:10.1167/iovs.17-22400.
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O'Brien CJ.

01

Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi:10.1167/iovs.17-22531.
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O'Brien CJ.

Showing 1 - 10 out of 10

01

Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi:10.1167/iovs.17-22531.
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O'Brien CJ.

02

Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi:10.1167/iovs.17-22400.
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O'Brien CJ.

03

Aging and ocular tissue stiffness in glaucoma.

Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O'Brien CJ.

04

The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.

Exp Eye Res. 2016 Jan;142:102-9.
Wallace DM, O'Brien CJ.

05

Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cell’.

Br J Ophthalmol.2015 Mar 20.pii: bjophthalmol-2014-306093.
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O'Brien CJ.

06

The role of matricellular proteins in glaucoma.

Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4.
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ.

07

Anticonnective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.

Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .

08

The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
Quill B, Docherty N, Clark AF, O'Brien CJ.

09

Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.

Mol Vis. 2011;17:1182-91.
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O'Brien CJ, Wallace DM

10

Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucoma

Kirwan RP, Wordinger RJ, Clark AF, O'Brien CJ.

Showing 1 - 10 out of 10

10

Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucoma

Kirwan RP, Wordinger RJ, Clark AF, O'Brien CJ.

09

Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.

Mol Vis. 2011;17:1182-91.
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O'Brien CJ, Wallace DM

08

The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
Quill B, Docherty N, Clark AF, O'Brien CJ.

07

Anticonnective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.

Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .

06

The role of matricellular proteins in glaucoma.

Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4.
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ.

05

Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cell’.

Br J Ophthalmol.2015 Mar 20.pii: bjophthalmol-2014-306093.
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O'Brien CJ.

04

The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.

Exp Eye Res. 2016 Jan;142:102-9.
Wallace DM, O'Brien CJ.

03

Aging and ocular tissue stiffness in glaucoma.

Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O'Brien CJ.

02

Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi:10.1167/iovs.17-22400.
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O'Brien CJ.

01

Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi:10.1167/iovs.17-22531.
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O'Brien CJ.