A. Specific Projects Related to Glaucoma Fibrosis.
- Bioenergetics and Mitochondrial Dysfunction in LC cells
- Role of Tissue Stiffness in TM and ONH, using integrin inhibitors
- Development of 3-D Lamina Cribrosa bio-engineered scaffold
- Proliferation and Apoptosis of LC fibroblasts
- Schlemm’s Canal Endothelial Cell Fibrosis
- Investigation of the role of YAP and Hippo Pathway
- Biodegradable anti-fibrotic drug-eluting scaffolds for post-glaucoma surgery sub-conjunctival fibrosis
- Use of single-cell RNA sequencing for differential gene expression
B. Pseudoexfoliation Glaucoma
- Role of DNA methylation in regulating LOXLI tissue expression
- Genotyping for risk determining SNPs in LOXLI
