Showing 1 - 180 out of 180
180
Imaten M, C.J.O’Brien
- 2023
- Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts.
- Int J Mol Sci. 2023 Jan 9;24(2):1287. doi 10.3390/jmis24021287
179
Symth A, Callaghan B, Willoughby CE, C.J O’Brien
- 2022
- The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy
- Int J Mol Sci. 2022 Sep 6:23(18):10216. doi:10.3390/ijms
178
P Murtagh, S Neary, C.J O’Brien
- 2022
- Screening for Glaucoma in Adults: Our Vision
- Ir MedJ 2022 Sept 15; 115(8):646
177
Murtagh P, O’Brien C.
- 2022
- Corneal Hysteresis, Intraocular Pressure and Progression of Glaucoma: Time for a “Hyst-Oric” Change in Clinical Practice?
- J Clin Med. 2022 May 20;11(10):2895. doi: 10.3390/jcm11102895
176
Hurley DJ, Normile C, Irnaten M, O’Brien C.
- 2022
- The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma.
- Antioxidants (Basel). 2022 Apr 29;11(5):886. doi: 10.3390/antiox11050886
175
Powell S, Irnaten M, O’Brien C.
- 2022
- Glaucoma – A Stiff Eye in a Stiff Body
- Curr Eye Res. 2022 Mar 7:1-9. doi: 10.1080/02713683.2022.2039204.
174
Powell S, Doolan E, Curtin K, Doyle A, O’Brien C.
- 2022
- Audit of outcomes following attendance at the City West drive-through IOP glaucoma clinic during COVID-19 pandemic.
- Ir J Med Sci. 2022 Jan 16:1-10. doi: 10.1007/s11845-021-02893-9.
173
Murphy R, Irnaten M, Hopkins A, O Callaghan J, Stamer WD, Clark AF, Wallace D, O’Brien CJ.
- 2022
- Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):16 doi: 10.1167/iovs.63.1.16.
172
Kelly RA, Perkumas KM, Campbell M, Farrar GJ, Stamer WD, Humphries P, O’Callaghan J, O’Brien CJ.
- 2021
- Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma.
- Int J Mol Sci. 2021 Aug 31;22(17):9446. Doi 10.3390/ijms22179446.
171
Hurley DJ, Iranaten, O’Brien C.
- 2021
- Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics.
- Cells 2021 Aug 19;10(8):2131. Doi: 10.3390/cells10082131.
170
O’Regan A, O’Brien CJ, Eivers SB.
- 2021
- The lysophosphatidic acid axis in fibrosis: Implications for glaucoma.
- Wound Repair Regen. 2021 Jul;29(4):613-626. doi: 10.1111/wrr.12929. Epub 2021 May 19.
169
Doolan E, O’Brien C.
- 2021
- Abnormal corneal properties in osteogenesis imperfect and glaucoma: a case series.
- BMJ Open Ophthalmic. 2021 Apr15;6(1):e000684 doi: 10.1136/bmjophth-2020-000684. eCollection 2021.
168
Kamel K, Dervan E, Falzon K, O’Brien C.
- 2020
- Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals.
- Ir J Med Sci. 2019 Feb;188(1):321-325. doi: 10.1007/s11845-018-1795-0. Epub 2018 Apr 4.
167
Cassidy PS, Kelly RA, Reina-Torres E, Sherwood JM, Humphries MM, Kiang AS, Farrar GJ, O’Brien C, Campbell M, Stamer WD, Overby DR, Humphries P, O’Callaghan J.
- 2020
- siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.
- Mol Ther Methods Clin Dev. 2020 Oct 31;20:86-94. doi: 10.1016/j.omtm.2020.10.022. eCollection 2021 Mar 12.
166
Greene AG, Eivers SB, McDonnell F, Dervan EWJ, O’Brien CJ, Wallace DM.
- 2020
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation.
- Exp Eye Res. 2020 Dec;201:108349. doi: 10.1016/j.exer.2020.108349. Epub 2020
165
Irnaten M, Duff A, Clark A, O’Brien C.
- 2020
- Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.
- J Clin Med. 2020 Dec 26;10(1):62. doi: 10.3390/jcm10010062.
164
Kamel K, O’Brien CJ, Zhdanov AV, Papkovsky DB, Clark AF, Stamer WD, Irnaten M.
- 2020
- Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):4. doi: 10.1167/iovs.61.13.4.
163
Hopkins AA, Murphy R, Irnaten M, Wallace DM, Quill B, O’Brien C.
- 2020
- The Role of Lamina Cribrosa Tissue Stiffness and Fibrosis as Fundamental Biomechanical Drivers of Pathological Glaucomatous Cupping.
- Am J Physiol Cell Physiol. 2020 Jul 15. doi: 10.1152/ajpcell.00054.2020.
162
Rahman N, O’Neill E, Irnaten M, Wallace D, O’Brien C.
- 2020
- Corneal Stiffness and Collagen Cross-Linking Proteins in Glaucoma: Potential for Novel Therapeutic Strategy.
- J Ocul Pharmacol Ther. 2020 Jul 13. doi: 10.1089/jop.2019.0118.
161
Eivers SB, Greene AG, Dervan E, O’Brien C, Wallace D
- 2020
- Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants Within Lysyl Oxidase-like 1 in an Irish Population.
- J Glaucoma. 2020 Jun;29(6):417-422. doi:10.1097/IJG.0000000000001475.
160
Iraten M, O’Malley G, Clark AF, O’Brien CJ.
- 2020
- Transient receptor potential channels TRPC1/TRPC6 regulate lamina cribrosa cell extracellular matrix gene transcription and proliferation.
- Exp Eye Res. 2020 Apr;193:107980. doi: 10.1016/j.exer.2020.107980. Epub 2020 Feb 20.
159
Greene AG, Eivers SB, Dervan EWJ,O’Brien CJ, Wallace DM.
- 2020
- Lysyl Oxidase Like 1: Biological roles and regulation.
- Exp Eye Res. 2020 Apr;193107975. doi:10.1016/j.exer.2020.107975. Epub 2020 Feb15.
158
Murtagh P, Greene G, O’Brien C.
- 2020
- Current application of machine learning in the screening and diagnosis of glaucoma: a systematic review and Meta-analysis.
- Int J Ophthalmic. 2020 Jan18;13(1):149-162
157
Bourke CM, Loughman J, Fltcroft DI, Loskutova E, O’Brien C.
- 2019
- We can't afford to turn a blind eye to myopia.
- QJM. 2019 Mar 26. pii: hcz076. doi: 10.1093/qjmed/hcz076.
156
Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, Kennedy C, Clerkin S, Doyle B, Godson C, Connell P, O’Brien C, Cagney G, Crean J.
- 2019
- Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.
- FASEB J. 2019 May;33(5):6667-6681. doi: 10.1096/fj.201800566RR
155
Loskutova E, O’Brien C, Loskutov I, Loughman J.
- 2018
- Nutritional supplementation in the treatment of glaucoma: A systematic review.
- Surv Ophthalmol. 2018 Oct 6. pii: S0039-6257(18)30100-0.
154
Kamel K, Bourke L, O’Brien C.
- 2018
- Clinical and Laboratory Biomarkers for Pseudoexfoliation Syndrome.
- J Glaucoma. 2018 Jul;27 Suppl 1:S111-S113.
153
Kamel K, Falzan K, Dervan E, O’Brien C.
- 2018
- Difference in intraocular pressure measurements between non-contact tonometry and Goldman applanation tonometry
- Ir J Med Sci. 2018
152
Barrett C, O’Brien C, Loughman J.
- 2018
- Glaucoma referral refinement in Ireland: managing the sensitivity-specificity paradox in optometric practice.
- Ophthalmic Physiol Opt. 2018 Feb 28. doi: 10.1111/opo.12446
151
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O’Brien C.
- 2018
- Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi: 10.1167/iovs.17-22531.
150
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O’Brien CJ.
- 2018
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi: 1
149
Siah WF, O’Brien C, Loughman JJ.
- 2017
- Macular pigment is associated with glare-affected visual function and central visual field loss in glaucoma.
- Br J Ophthalmol. 2017 Oct 5. pii: bjophthalmol-2017-310215. doi: 10.1136/bjophthalmol-2017-310215. [Epub ahead of print]
148
Kamel K, Farrell M, O’Brien C.
- 2017
- Mitochondrial dysfunction in ocular disease: Focus on glaucoma.
- Mitochondrion. 2017 Jul;35:44-53. doi: 10.1016/j.mito.2017.05.004. Epub 2017 May 9.
147
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O’Brien CJ.
- 2017
- Aging and ocular tissue stiffness in glaucoma.
- Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
146
Barrett C, O’Brien C, Butler JS, Loughman J.
- 2017
- Barriers to glaucoma case finding as perceived by optometrists in Ireland.
- Clin Exp Optom. 2017 Jul 17. doi: 10.1111/cxo.12573.
145
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95. doi: 10.1089/jop.2014.0163. Epub 2015 Apr 7. Review.
144
O’Callaghan J, Crosbie DE, Cassidy PS, Sherwood JM, Flügel-Koch C, Lütjen-Drecoll E, Humphries MM, Reina-Torres E, Wallace D, Kiang AS, Campbell M, Daniel SW, Overby DR, O’Brien C, Tam LC, Humphries P.
- 2017
- Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.
- Hum Mol Genet. 2017 Feb 1. doi: 10.1093/hmg/ddx028.
143
Murphy ML, Pokrovskaya O, Galligan M, O’Brien C.
- 2017
- Corneal hysteresis in patients with glaucoma-like optic discs, ocular hypertension and glaucoma.
- BMC Ophthalmol. 2017 Jan 10;17(1):1. doi: 10.1186/s12886-016-0396-9.
142
McDonnell FS, McNally SA, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells.
- J Glaucoma. 2016 Oct;25(10):e834-e842.
141
Paula JS, O’Brien C, Stamer WD.
- 2016
- Life under pressure: The role of ocular cribriform cells in preventing glaucoma.
- Exp Eye Res. 2016 Oct;151:150-9. doi: 10.1016/j.exer.2016.08.014. Epub 2016 Aug 25. Review.
140
Treacy MP, O’Neill EC, Murphy M, O’Toole L, Delaney Y, O’Brien C, Connell PP.
- 2016
- Opportunistic detection of glaucomatous optic discs within a diabetic retinopathy screening service.
- Eur J Ophthalmol. 2016 Jun 10;26(4):315-20. doi: 10.5301/ejo.5000722. Epub 2015 Dec 17.
139
McDonnell F, Irnaten M, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.
- PLoS One. 2016 Apr 28;11(4):e0153354. doi: 10.1371/journal.pone.0153354. eCollection 2016 Apr 28.
138
Pokrovskaya O, O’Brien C.
- 2016
- What's in a Gene? Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient.
- Case Rep Ophthalmol. 2016 Jan 21;7(1):54-60. doi: 10.1159/000443697. eCollection 2016 Jan 21.
137
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR.
- 2016
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2016 Feb;25(2):e99-e105.
136
O’Brien C, Clark AF.
- 2016
- Introduction to EER Special Issue on ocular fibrosis.
- Exp Eye Res. 2016 Jan;142:1.
135
Wallace DM, O’Brien CJ. The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- 2016
- The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- Exp Eye Res. 2016 Jan;142:102-9.
134
Quill B, Henry E, Simon E, O’Brien CJ.
- 2015
- Evaluation of the Effect of Hypercapnia on Vascular Function in Normal Tension Glaucoma.
- Biomed Res Int. 2015;2015:418159.
133
Siah WF, Loughman J, O’Brien C.
- 2015
- Lower Macular Pigment Optical Density in Foveal-Involved Glaucoma.
- Ophthalmology. 2015 Oct;122(10):2029-37.
132
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95.
131
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR
- 2015
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2015 Apr 21. [Epub ahead of print]
130
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The function of matricellular proteins in the lamina cribrosa and trabecular meshwork in glaucoma.
- J Ocul Pharmacol Ther. 2015 Apr 7. [Epub ahead of print]
129
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O’Brien CJ
- 2015
- ‘Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cells’.
- Br J Ophthalmol. 2015 Mar 20. pii: bjophthalmol-2014-306093. doi: 10.1136/bjophthalmol-2014-306093. [Epub ahead of print]
128
McElnea EM, Hughes E, McGoldrick A, McCann A, Quill B, Docherty N, Irnaten M, Farrell M, Clark AF, O’Brien CJ, Wallace DM.
- 2014
- Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells.
- BMC Ophthalmol. 2014 Dec 2;14:153.
127
McNally S, O’Brien CJ. Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
- 2014
- Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma.
- J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
126
Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O’Brien C, McKnight AJ, Willoughby CE
- 2014
- Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.
- Genet Med. 2014 Sep 18.
125
Gao W, Ferguson G, Connell P, Walshe T, O’Brien C, Redmond EM, Cahill PA.
- 2014
- Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression.
- Diab Vasc Dis Res. 2014 May 22;11(4):270-280.
124
McDonnell F, O’Brien C, Wallace D.
- 2014
- The role of epigenetics in the fibrotic processes associated with glaucoma.
- J Ophthalmol. 2014~:750459.
123
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ
- 2014
- The role of matricellular proteins in glaucoma.
- Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4
122
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .
- 2013
- Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.
- Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
121
Irnaten M, Barry RC, Wallace DM, Docherty NG, Quill B, Clark AF, O’Brien CJ.
- 2013
- Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells
- Exp Eye Res 2013 Oct; 115:224-9
120
Igras E, Loughman J, Ratzlaff M, O’Caoimh R, O’Brien C.
- 2013
- Evidence of lower macular pigment optical density in chronic open angle glaucoma. Br J Ophthalmol. 2013 Aug;97(8):994-998
- Br J Ophthalmol. 2013 Aug;97(8):994-998
119
Bhattacharya SK, Lee RK, Grus FH;
- 2013
- Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group. Molecular biomarkers in glaucoma.
- 2013 Jan 7;54(1):121-31
118
Kirwan RP, Felice L, Clark AF, O’Brien CJ, Leonard MO.
- 2012
- Hypoxia regulated gene transcription in human optic nerve lamina cribrosa cells in culture.
- Invest Ophthalmol Vis Sci. 2012 53:2243-2255
117
Wiggs JL, Hewitt AW, Fan BJ, Wang DY, Figueiredo Sena DR, O’Brien C, Realini A, Craig JE, Dimasi DP, Mackey DA, Haines JL, Pasquale LR.
- 2012
- The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.
- PLoS One. 2012;7(9):e45613. doi: 10.1371/journal.pone.0045613. Epub 2012 Sep 26
116
Walshe TE, Connell P, Cryan L, Ferguson G, Gardiner T, Morrow D, Redmond EM, O’Brien C, Cahill PA
- 2011
- Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch signaling.
- Invest Ophthalmol Vis Sci. 2011 . Jun 23;52(7):4472-83.
115
Browne JG, Ho SL, Kane R, Oliver N, Clark AF, O’Brien CJ, Crean JK.
- 2011
- Connective Tissue Growth Factor is increased in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3660-6
114
Gallagher BA, Hart PM, O’Brien C, Stevenson MR, Jackson AJ.
- 2011
- Mobility and access to transport issues as experienced by people with vision impairment living in urban and rural Ireland.
- Disabil Rehabil. 2011;33(12):979-88.
113
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O’Brien CJ, Wallace DM
- 2011
- Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.
- Mol Vis. 2011;17:1182-91.
112
Guerin M, Cotter T, McKernan D, O’Brien C.
- 2011
- Age Dependent Rat Retinal Ganglion Cell Susceptibility to Apoptotic Stimuli: Implications for Glaucoma.
- Clin & Exper Ophthalmol Apr;39(3):243-51. 2011
111
Quill B, Docherty N, Clark AF, O’Brien CJ.
- 2011
- The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
110
Farrell SM, Groeger G, Bhatt L, Finnegan S, O’Brien CJ, Cotter TG.
- 2011
- bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.
- Eur J Neurosci. 2011 Feb;33(4):632-41.
109
Walshe TE, Connell P, Cryan L, Ferguson G, O’Brien C, Cahill PA.
- 2011
- The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation.
- Cardiovasc Res. 2011 Feb 15;89(3):661-70.
108
P O’Connor R, Cryan LM, Wynne K, de Stefani A, Fitzgerald D, O’Brien C, Cagney G.
- 2010
- Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.
- J Biomed Biotechnol. 2010; 2010:107859.
107
Dervan EW, Chen H, Ho SL, Brummel N, Schmid J, Toomey D, Haralambova M, Gould E, Wallace DM, Prehn JH, O’Brien C, Murphy D.
- 2010
- Protein Macroarray Profiling of Serum Autoantibodies in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2968-75.
106
Quaranta L, Konstas AG, Rossetti L, Garcia-Feijoo J, O’Brien C, Nasr MB, Fogagnolo P, Demos CM, Stewart JA, Stewart WC.
- 2010
- Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry.
- Eye (Lond). 2010 Jul;24(7):1252-8. Epub 2009 Dec 4.
105
Kirwan RP, Wordinger RJ, Clark AF, O’Brien CJ.
- 2009
- Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells.
- Mol Vis. 2009;15:76-88. Epub 2009 Jan 15.
104
Irnaten M, Barry RC, Quill B, Clark AF, Harvey BJ, O’Brien CJ.
- 2009
- Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells.
- Invest Ophthalmol Vis Sci. 2009 Jan;50(1):194-202. Epub 2008 Sep 4.
103
Cryan L, Fitzgerald D, O’Brien C.
- 2009
- Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclogenase.
- Prostaglandins, Leuko & Essent Fatty Acids 2009 81:401-9.
102
Guerin M, Flynn T, Brady J, O’Brien C.
- 2008
- Worldwide geographical distribution of ophthalmic publications.
- Int Ophthalmol; 2008; 29: 511-6.
101
Cryan L, O’Brien C.
- 2008
- Proteomics as a research tool in clinical and experimental ophthalmology.
- Proteomics Clin. App. 2008; 2(5); 762-75
100
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O’Brien C, Walls D, Redmond EM, Cahill PA.
- 2008
- Notch and vascular smooth muscle cell phenotype.
- Circ Res. 2008 Dec 5;103(12):1370-82.
099
O’Connor JC, Wallace DM, O’Brien C, Cotter TG. A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- 2008
- A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4237-44
098
Kane R, Godson C, O’Brien C.
- 2008
- Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
- Mol Vis. 2008 Jun 20;14:1138-48.
097
O’Driscoll C, O’Connor J, O’Brien CJ, Cotter TG.
- 2008
- Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
- J Neurochem. 2008 Apr;105(2):524-36. Epub 2007 Dec 13.
096
Aragon-Martin JA, Ritch R, Liebmann J, O’Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Damji KF, Tarkkanen A, Rezaie T, Child AH, Sarfarazi M.
- 2008
- Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
- Mol Vis. 2008 Mar 17;14:533-41.
095
Cryan LM, Paraoan L, Hiscott P, Damato BE, Grierson I, Gray D, Farrell M, Doherty GA, Fitzgerald DJ, O’Brien C.
- 2008
- Expression of COX-2 and prognostic outcome in uveal melanoma.
- Curr Eye Res. 2008 Feb;33(2):177-84.
094
Horgan N, Kirwan RP, O’Brien CJ.
- 2007
- Choroidal detachment associated with latanoprost use in the fellow eye.
- Ann Pharmacother. 2007 Jan;41(1):161-2.
093
Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O’Brien C, Cahill PA.
- 2007
- High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.
- J Mol Cell Cardiol. 2007 Mar;42(3):609-19. Epub 2006 Dec 21.
092
Connell P, Walshe T, Ferguson G, Gao W, O’Brien C, Cahill PA.
- 2007
- Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells.
- Endothelium. 2007 Jan-Feb;14(1):17-24.
091
Lee H, O’Meara SJ, O’Brien C, Kane R.
- 2007
- The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy.
- Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4291-9.
090
McKernan DP, Guerin MB, O’Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death.
- 2007
- Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5420-30.
089
Guerin MB, McKernan DP, O’Brien CJ, Cotter TG.
- 2006
- Retinal ganglion cells: dying to survive.
- Int J Dev Biol. 2006;50(8):665-74..
088
Y Delaney, T Walshe, C O’Brien.
- 2006
- Vasospasm in glaucoma: clinical and laboratory aspects.
- Optom Vis Sci. 2006 Jul;83(7):406-14.
087
E Henry, D Newby, DJ Webb, PW Hadoke, C O’Brien.
- 2006
- Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma.
- Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2528-32.
086
L Cryan, G Pidgeon, D Fitzgerald, C O’Brien.
- 2006
- COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
- Mol Vis. 2006 Apr 20;12:405-14
085
C Kelliher, D Kenny, C O’Brien.
- 2006
- Trends in blind registration in the adult population of the Republic of Ireland. 1996-2003.
- Br J Ophthalmol 2006 Mar;90(3)367-71.
084
McKernan DP, Caplis C, Donovan M, O’Brien C, Cotter T.
- 2006
- Age-dependent susceptibility of the retinal ganglion cell layer to cell death.
- Invest Ophthalmol Vis Sci. 2006 Mar;47(3):807-14.
083
A Knox, M Barry, C O’Brien.
- 2006
- The rising cost of glaucoma drugs in Ireland. 1996-2003.
- Br J Ophthalmol 2006 Feb;90(2):162-5
082
R Kane, L Stevenson, C Godson, A Stitt, C O’Brien.
- 2005
- Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose.
- Br J Ophthalmol 2005; Dec;89(12): 1638-42
081
R Kirwan, C Fenerty, J Crean, R Wordinger, A F Clark, C O’Brien
- 2005
- Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro.
- Mol Vis 2005 Sep 23;11:798-810
080
R Kirwan, M O’Leonard, M Murphy A F Clark, C O’Brien
- 2005
- Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells.
- Glia. 2005 Dec;52(4):309-24.
079
VW Long, C O’Brien.
- 2005
- Trends in ophthalmic surgery in Ireland.
- Irish Journal Med. Sci 2005; 174 (2); 36-39
078
P Aspinall, A Hill, P Nelson, C O’Brien, E O’Connell, L McCloughan, A Azuara-Blanco, R Brice, S Green, C Steeds.
- 2005
- Quality of life in patients with glaucoma: a conjoint analysis approach.
- Visual Impairment Research 2005; 7 (1): 13-26.
077
T E Walshe, G Ferguson, P Connell, C O’Brien, P A Cahill.
- 2005
- Pulsatile flow increases the expression of eNOS, ET-1, and Prostacyclin in a novel in vitro coculture model of the retinal vasculature.
- Invest Ophthal Vis Sci 2005;Jan(46)1:375-382.
076
C Cleary, C H Buckley, E Henry, P McLoughlin, C O’Brien, P W Hadoke.
- 2005
- Enhanced endothelium derived hyperpolarized factor activity in resistance arteries from normal pressure glaucoma patients: implications for vascular function in the eye.
- Br J Ophthalmol 2005;89:223-228
075
S L Ho, G F Dogar, J Wang, J Crean, Q D Wu, N Oliver, S Weitz, A Murray, P E Cleary, C O’Brien.
- 2005
- Elevated aqueous humour tissue inhibitor of matrix metalloproteinase-1 and connective tissue growth factor in pseudoexfoliation disease.
- Br J Ophthalmol 2005;89:169-173.
074
Morgan-Davies J, Taylor N, Hill AR, Aspinall P, O’Brien CJ, Asuara-Blanco A.
- 2004
- Three dimensional analysis of the lamina cribrosa in glaucoma.
- Br J Ophthalmol 2004 Oct;88(10): 1299-304.
073
R Kirwan, J Crean, C Fenerty, A Clark, C O’Brien.
- 2004
- Effect of cyclical mechanical stretch and exogenous transforming growth factor-B1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
- J Glaucoma 2004 Aug; 13(4): 327-34.
072
J Stokes, R Best, C O’Brien, J Seckl.
- 2003
- Altered glucocorticoid peripheral sensitivity in glaucoma.
- Invest Ophthal Vis Sci 2003; Dec 44(12) 5163-7.
071
J Kerr, C O’Brien.
- 2003
- Ocular blood flow in untreated ocular hypertension.
- Am J Ophthalmology 2003 Dec 136(6) 1106-13.
070
S Quinn, C O’Brien, P McLoughlin.
- 2003
- Nitric oxide independent vasorelaxation in the bovine long posterior ciliary artery.
- Eye 2003 July 17(5) 628-36.
069
P Nelson, P Aspinall, C O’Brien.
- 2003
- The relationship between quality of life and visual function in glaucoma.
- J Glaucoma 2003 Apr 12(2) 139-50.
068
Buckley C, Hadoke P, Henry E, O’Brien C.
- 2002
- Systemic vascular endothelial dysfunction in normal pressure glaucoma
- Br J Ophthalmology 2002; 86; 227-32.
067
O’Toole L, Cahill M, O’Brien C.
- 2001
- Eyelid hypertrichosis associated with latanoprost is reversible.
- Eur J Ophthalmol. 2001 Oct-Dec;11(4):377-9.
066
Devlin H, O’Brien C.
- 2001
- Normal tension glaucoma: Diagnosis and Management.
- CME Journal Ophthalmol 2001; 5(1): 13-17.
065
Morgan-Davies J, King A, Aspinall P, O’Brien C.
- 2000
- Measurement of a novel optic disc topographic parameter ‘spikiness’ in glaucoma.
- Graefe’s Arch Clin Exp Ophthalmol 2000, 238: 669- 76.
064
McKinnon J, McKillop G, Swa K, O’Brien C, Butt Z, Nelson P.
- 2000
- Colour Doppler imaging of the ocular circulation in diabetic retinopathy.
- Acta Ophthalmol, 2000, 78: 386-9.
063
Stokes J, Andrew R, Seckyl J, O’Brien C.
- 2000
- Glucocorticoid and mineralocorticoid receptors and 11-beta-deyhydrogenase activity in rat and human ocular tissue.
- Invest Ophthalmol Vis Sci 2000; 41: 1629-38.
062
King A, Bolton N, Aspinall P, O’Brien C.
- 2000
- Retinal nerve fibre layer volume in glaucoma.
- Am J Ophthalmol 2000, 129: 599-607.
061
J Stokes, E Henry, C O’Brien.
- 1998/1999
- Differential Diagnosis of Normal Tension Glaucoma (1998)
- In: Pillunat L, Harris A (eds) Fortbildurg Glaucoma. Enke Verlag, Stuggart, 1999.
060
O’Brien C, Butt Z.
- 1999
- Blood flow velocity in the peripheral circulation of glaucoma patients.
- Ophthalmologica 1999; 213: 150-153.
059
Henry E, Newby DE, Webb DJ, O’Brien C.
- 1999
- Peripheral endothelial dysfunction in normal pressure glaucoma.
- Invest Ophthalmol Vis Sci 1999; 40: 1710-1714.
058
Nelson P, Aspinall P, O’Brien C.
- 1999
- Patients’ perception of visual impairment in glaucoma. A pilot study.
- Br J Ophthalmol 1999; 83: 546-552.
057
Edgar DF, Crabb DP, Rudnicka AR, Lawrensen JG, Gutteridge NM, O’Brien C.
- 1999
- Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and Logmar acuity.
- Graefe’s Arch Clin Exp Ophthalmol 1999; 237: 117-24.
056
Buckley C H, Hadoke P, O’Brien C.
- 1998
- Role of the endothelium in modulating functional responses of isolated bovine anterior ciliary arteries to vasoconstrictor agonists.
- Br J Ophthalmol 1998; 82: 826-829.
055
Fontana L, Poinoosawmy D, Bunce CV, O’Brien C, Hitchings RA.
- 1998
- Pulsatile ocular blood flow investigation in asymmetric normal-tension glaucoma and normal subjects.
- Br J Ophthalmol 1998; 82: 731-6.
054
Kelly PA, Buckley C, Ritchie IM, O’Brien C.
- 1998
- Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat.
- Br J Ophthalmol 1998; 82: 1199-202.
053
O’Brien C
- 1998
- Vasospasm and glaucoma (Editorial).
- Br J Ophthalmol 1998; 82: 855-6.
052
Kerr J, Nelson P, O’Brien C.
- 1998
- A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension.
- Am J Ophthalmol 1998; 126: 42-51.
051
C. O’Brien.
- 1998
- Is there a role for computerised image analysis in glaucoma management.
- Br. J Ophthalmol 1998, 82: 2-3. (Editorial).
050
C Buckley, P Hadoke, C O’Brien.
- 1997
- The use of isolated ocular arteries in-vitro to define the pathology of vascular changes in glaucoma.
- Br J Ophthalmol 1997, 81:599 - 607
049
JR Mackinnon, Z Butt, K Swa, C O’Brien.
- 1997
- Pulsatile ocular blood flow in untreated diabetic retinopathy.
- Acta Ophthalmol, 1997; 75:6, 661-4.
048
RWD Bell, NE Habib, C O’Brien.
- 1997
- Long-term outcome and complications of trabeculectomy with a single per-operative application of 5-fluorouracil.
- Eye 1997;11: 663-71.
047
RS Anderson, C O’Brien.
- 1997
- Psychophysical evidence for selective loss of M ganglion cells in glaucoma
- Vis Res 1997 , 37: 1079-1083.
046
RWD Bell, HK Yang, C O’Brien.
- 1997
- A case of bilateral cavernous hemangioma associated with intra-cerebral hemangioma.
- Arch Ophthalmol 1997, 115:6, 818-9.
045
C O’Brien, Z Butt, C Ludlum.
- 1997
- Activation of the coagulation cascade in untreated primary open angle glaucoma.
- Ophthalmol 1997; 104:725 - 730
044
Z Butt, C O’Brien, G McKillop, P Aspinall, P Allan.
- 1997
- Colour Doppler imaging in untreated high and normal pressure open angle glaucoma.
- Invest Ophthalmol Vis Sci, 1997; 38: 690-6.
043
C O’Brien, P Kelly, I Ritchie.
- 1997
- The effect of chronic inhibition of nitric oxide synthase on ocular blood flow and glucose metabolism in rats.
- Br J Ophthalmol 1997;81:68-71.
042
RWD Bell, C O’Brien.
- 1997
- Accuracy of referral to a glaucoma clinic.
- Ophthal Physiol Opt 1997;17:7-11.
041
RWD Bell, C O’Brien.
- 1997
- Diagnostic outcome of hospital glaucoma referrals.
- Ophthal Physiol Opt 1997;17:3-6.
040
A Kosmin, M Austin, C.O’Brien, N. Cotu, P. Wishart.
- 1996/1997
- Ageing changes in automated perimetry. A comparison of flicker and luminance sensitivity in normal subjects.
- In: Wall M, Heijl A (eds). Perimetry update 1996/1997. Kugler: Amsterdam, New York 1997, pp 229 - 233.
039
FD Ghanchi, TH Williamson, CS Lim, Z Butt, GM Baxter, G McKillop, C O’Brien.
- 1996
- Colour Doppler imaging in giant cell (temporal) arteritis: serial examination and comparison with non-arteritic anterior ischaemic optic neuropathy.
- Eye 1996;10:459-464.
038
C Lim, C O’Brien, N Bolton.
- 1996
- A simple clinical method to measure the optic disc size in glaucoma.
- J Glaucoma 1996;5:241-245.
037
J Sing, R Bell, A Adams, C O’Brien,
- 1996
- Enhancement of post trabeculectomy bleb formation by laser suture lysis.
- Br J Ophthalmol 1996;80:624-627.
036
RS Ayyala, C O’Brien, I Grierson, P Maltby.
- 1996
- Transcleral flow of aqueous humor: an in-vitro experiment.
- Ophthalmol Surg 1996;27:66-69.
035
M Birch, S Barbosa, L Blumhardt, C O Brien, S Harding.
- 1996
- Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis.
- Arch Ophthalmol 1996;114-119.
034
RS Anderson, P Detkova, C O’Brien.
- 1995
- Effect of temporal frequency and contrast on peripheral grating resolution.
- Curr Eye Res 1995;14:1031-1033.
033
GP Rao, C O’Brien, MH Dwyer, A Patterson.
- 1995
- Rapid onset bilateral calcific band keratopathy associated with phosphate containing steroid eye drops.
- Eur J Implant Refr Surg 1995;7:251-252.
032
A King, D David, H Jones, C O’Brien.
- 1995
- Non-attendance at an ophthalmic out-patient department.
- J Roy Soc Med 1995;88:88-90.
031
J Sing, H Chawla, C O’Brien.
- 1995
- Success rate and complications of intraoperative mitomycin-C in trabeculectomy surgery.
- Eye 1995;9:460-466.
030
Z Butt, C O’Brien.
- 1995
- Reproducibility of pulsatile ocular blood flow measurements.
- J Glaucoma 1995;4:214-218.
029
C O’Brien, J Wild.
- 1995
- Automated perimetry in glaucoma - room for improvement?
- Br J Ophthalmol 1995;79:200-201. (editorial)
028
Z Butt, G McKillop, C O’Brien, P Allan, P Aspinall.
- 1995
- Measurement of ocular blood flow velocity using colour Doppler imaging in low tension glaucoma.
- Eye 1995, 9:29-33.
027
D. Broadway, I Grierson, C O’Brien, R Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part II. The outcome of filtration surgery.
- Arch Ophthalmol 1994;112:1446-1454.
026
D Broadway, I Grierson, C O’Brien, RA Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part I. The conjunctival cell profile.
- Arch Ophthalmol 1994;112:1437-1445.
025
C de Vivero, C O’Brien, L Lanigan, RA Hitchings.
- 1994
- Diurnal intraocular pressure variation in low tension glaucoma.
- Eye 1994;8:521-523.
024
C O’Brien, D Clark.
- 1994
- Ocular biometry in preterm infants without retinopathy of prematurity.
- Eye 1994;8:662-665.
023
M Austin, C O’Brien, P Wishart.
- 1994
- Flicker perimetry using a luminance threshold strategy at frequencies from 5-25Hz in glaucoma, ocular hypertension and normal controls.
- Curr Eye Res 1994;13:7171-724.
022
DE Laws, R Haslett, D Ashby, C O’Brien, D Clark.
- 1994
- Axial length biometry in infants with retinopathy of prematurity.
- Eye 1994;8:427-430.
021
C O’Brien, D Poinoosawmy, J Wu, R Hitchings.
- 1994
- Evaluation of a rapid thresholding program (Fastpac) in glaucoma.
- Br J Ophthalmol 1994;78:516-9.
020
MW Austin, C O’Brien, PE Wishart.
- 1994/1995
- Forced choice flicker perimetry in glaucoma.
- In: Perimetry Update 1994/1995; (eds) RP Mills, M Wall. Kugler Publ, Amsterdam, pp 135-140.
019
K. Evans, C O’Brien, A Patterson.
- 1994
- Corneal endothelial response to corticosteroid in cataract surgery.
- Eur J Implant Refr Surg 1994;6:74-78.
018
B Moriarty, C O’Brien.
- 1993
- Cataract surgery in the glaucoma patient.
- In: Ball S, Franklin R (eds); Trans New Orleans and Acad Ophthalmol - Glaucoma, Diagnosis and Therapy 1993. Kugler Publ, Amstelveen pp 159-168.
017
J. Singh, C O’Brien, M Wright.
- 1993
- Nebulised bronchodilator therapy causes acute angle closure glaucoma in predisposed individuals.
- Resp Med 1993, 187:559-561
016
C O’Brien, JD Young, M Brown, C Short, M Bone.
- 1993
- Electrophysiology of type 2 mesangio-capillary glomerulonephritis with associated fundus abnormalities.
- Br J Ophthalmol 1993;77:778-780.
015
L Lanigan, C O’Brien, R Hitchings.
- 1992
- “Bubble sight”.
- BMJ (Minerva) 1992;305:1588.
014
M Cox, C. O’Brien.
- 1992
- Comparison of computer assisted versus manual optic nerve head pallor measurement.
- Invest Ophthalmol Vis Sci 1992;33:3169-3173.
013
D. Clark, C O’Brien, M Weindling, M Saed.
- 1992
- Initial experience of screening for retinopathy of prematurity.
- Arch Dis Child 1992;67:1233-1236.
012
C. O’Brien, V Saxton, RP Crick, HB Meire.
- 1992
- Doppler carotid artery studies in asymmetric glaucoma.
- Eye 1992;6:273-276
011
D. Poinoosawmy, J Sturmer, C O’Brien, J Wu, R Hitchings.
- 1992
- Is diffuse visual field loss in low tension glaucoma a prognostic indicator for progression.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ. Amsterdam, pp 121-127.
010
C O’Brien, M Austin, P Wareing, P Hammond.
- 1992
- Clinical evaluation of a new combined automated flicker and static perimeter.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ: Amsterdam, pp 603-606.
009
C O’Brien, B Schwartz.
- 1992
- Point by point linear regression analysis of automated visual fields in chronic open angle glaucoma.
- In: Perimetry Update 1992/93; Mills RP (ed). Kugler Publ, Amsterdam, pp 149-152.
008
C. O’Brien, B Schwartz, T Takamoto.
- 1991
- Correlation of optic disc cupping, pallor and retinal nerve fibre layer thickness with visual field loss in chronic open angle glaucoma.
- In: Perimetry Update 1991; eds Mills and Heijl: Kugler Publ, Amsterdam pp15-19.
007
C. O’Brien. Optic disc pallor measurement.
- 1991
- Optic disc pallor measurement.
- Eye 1991;5:763.
006
J. Butcher, C. O’Brien.
- 1991
- The reproducibility of biometry and keratometry.
- Eye 1991;5:708-711.
005
C. O’Brien, B Schwartz, T Takamoto, DC Wu.
- 1991
- Intraocular pressure and the rate of change of the visual field in chronic open angle glaucoma.
- Am J Ophthalmol 1991;111:491-497.
004
McAllister, C. O’Brien. Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- 1990
- Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- Eye 1990;4:651-654.
003
C. O’Brien, B Schwartz. The visual field in chronic open angle glaucoma:
- 1990
- The visual field in chronic open angle glaucoma: the rate of change in the different regions of the field.
- Eye 1990;4:557-562.
002
CJ O’Brien, I Grierson, J McAllister. Treatment parameters for
- 1990
- transcleral cyclocoagulation with the Neodymium:Yag laser.
- Lasers Ophthalmol 1990;3:221-225.
001
C J O’Brien, GM Kyle
- 1988
- Metastatic staphylococcus aureas endophthalmitis:
- Br J Ophthalmol 1988;72:189-91.
Showing 1 - 180 out of 180
001
C J O’Brien, GM Kyle
- 1988
- Metastatic staphylococcus aureas endophthalmitis:
- Br J Ophthalmol 1988;72:189-91.
002
CJ O’Brien, I Grierson, J McAllister. Treatment parameters for
- 1990
- transcleral cyclocoagulation with the Neodymium:Yag laser.
- Lasers Ophthalmol 1990;3:221-225.
003
C. O’Brien, B Schwartz. The visual field in chronic open angle glaucoma:
- 1990
- The visual field in chronic open angle glaucoma: the rate of change in the different regions of the field.
- Eye 1990;4:557-562.
004
McAllister, C. O’Brien. Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- 1990
- Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- Eye 1990;4:651-654.
005
C. O’Brien, B Schwartz, T Takamoto, DC Wu.
- 1991
- Intraocular pressure and the rate of change of the visual field in chronic open angle glaucoma.
- Am J Ophthalmol 1991;111:491-497.
006
J. Butcher, C. O’Brien.
- 1991
- The reproducibility of biometry and keratometry.
- Eye 1991;5:708-711.
007
C. O’Brien. Optic disc pallor measurement.
- 1991
- Optic disc pallor measurement.
- Eye 1991;5:763.
008
C. O’Brien, B Schwartz, T Takamoto.
- 1991
- Correlation of optic disc cupping, pallor and retinal nerve fibre layer thickness with visual field loss in chronic open angle glaucoma.
- In: Perimetry Update 1991; eds Mills and Heijl: Kugler Publ, Amsterdam pp15-19.
009
C O’Brien, B Schwartz.
- 1992
- Point by point linear regression analysis of automated visual fields in chronic open angle glaucoma.
- In: Perimetry Update 1992/93; Mills RP (ed). Kugler Publ, Amsterdam, pp 149-152.
010
C O’Brien, M Austin, P Wareing, P Hammond.
- 1992
- Clinical evaluation of a new combined automated flicker and static perimeter.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ: Amsterdam, pp 603-606.
011
D. Poinoosawmy, J Sturmer, C O’Brien, J Wu, R Hitchings.
- 1992
- Is diffuse visual field loss in low tension glaucoma a prognostic indicator for progression.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ. Amsterdam, pp 121-127.
012
C. O’Brien, V Saxton, RP Crick, HB Meire.
- 1992
- Doppler carotid artery studies in asymmetric glaucoma.
- Eye 1992;6:273-276
013
D. Clark, C O’Brien, M Weindling, M Saed.
- 1992
- Initial experience of screening for retinopathy of prematurity.
- Arch Dis Child 1992;67:1233-1236.
014
M Cox, C. O’Brien.
- 1992
- Comparison of computer assisted versus manual optic nerve head pallor measurement.
- Invest Ophthalmol Vis Sci 1992;33:3169-3173.
015
L Lanigan, C O’Brien, R Hitchings.
- 1992
- “Bubble sight”.
- BMJ (Minerva) 1992;305:1588.
016
C O’Brien, JD Young, M Brown, C Short, M Bone.
- 1993
- Electrophysiology of type 2 mesangio-capillary glomerulonephritis with associated fundus abnormalities.
- Br J Ophthalmol 1993;77:778-780.
017
J. Singh, C O’Brien, M Wright.
- 1993
- Nebulised bronchodilator therapy causes acute angle closure glaucoma in predisposed individuals.
- Resp Med 1993, 187:559-561
018
B Moriarty, C O’Brien.
- 1993
- Cataract surgery in the glaucoma patient.
- In: Ball S, Franklin R (eds); Trans New Orleans and Acad Ophthalmol - Glaucoma, Diagnosis and Therapy 1993. Kugler Publ, Amstelveen pp 159-168.
019
K. Evans, C O’Brien, A Patterson.
- 1994
- Corneal endothelial response to corticosteroid in cataract surgery.
- Eur J Implant Refr Surg 1994;6:74-78.
020
MW Austin, C O’Brien, PE Wishart.
- 1994/1995
- Forced choice flicker perimetry in glaucoma.
- In: Perimetry Update 1994/1995; (eds) RP Mills, M Wall. Kugler Publ, Amsterdam, pp 135-140.
021
C O’Brien, D Poinoosawmy, J Wu, R Hitchings.
- 1994
- Evaluation of a rapid thresholding program (Fastpac) in glaucoma.
- Br J Ophthalmol 1994;78:516-9.
022
DE Laws, R Haslett, D Ashby, C O’Brien, D Clark.
- 1994
- Axial length biometry in infants with retinopathy of prematurity.
- Eye 1994;8:427-430.
023
M Austin, C O’Brien, P Wishart.
- 1994
- Flicker perimetry using a luminance threshold strategy at frequencies from 5-25Hz in glaucoma, ocular hypertension and normal controls.
- Curr Eye Res 1994;13:7171-724.
024
C O’Brien, D Clark.
- 1994
- Ocular biometry in preterm infants without retinopathy of prematurity.
- Eye 1994;8:662-665.
025
C de Vivero, C O’Brien, L Lanigan, RA Hitchings.
- 1994
- Diurnal intraocular pressure variation in low tension glaucoma.
- Eye 1994;8:521-523.
026
D Broadway, I Grierson, C O’Brien, RA Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part I. The conjunctival cell profile.
- Arch Ophthalmol 1994;112:1437-1445.
027
D. Broadway, I Grierson, C O’Brien, R Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part II. The outcome of filtration surgery.
- Arch Ophthalmol 1994;112:1446-1454.
028
Z Butt, G McKillop, C O’Brien, P Allan, P Aspinall.
- 1995
- Measurement of ocular blood flow velocity using colour Doppler imaging in low tension glaucoma.
- Eye 1995, 9:29-33.
029
C O’Brien, J Wild.
- 1995
- Automated perimetry in glaucoma - room for improvement?
- Br J Ophthalmol 1995;79:200-201. (editorial)
030
Z Butt, C O’Brien.
- 1995
- Reproducibility of pulsatile ocular blood flow measurements.
- J Glaucoma 1995;4:214-218.
031
J Sing, H Chawla, C O’Brien.
- 1995
- Success rate and complications of intraoperative mitomycin-C in trabeculectomy surgery.
- Eye 1995;9:460-466.
032
A King, D David, H Jones, C O’Brien.
- 1995
- Non-attendance at an ophthalmic out-patient department.
- J Roy Soc Med 1995;88:88-90.
033
GP Rao, C O’Brien, MH Dwyer, A Patterson.
- 1995
- Rapid onset bilateral calcific band keratopathy associated with phosphate containing steroid eye drops.
- Eur J Implant Refr Surg 1995;7:251-252.
034
RS Anderson, P Detkova, C O’Brien.
- 1995
- Effect of temporal frequency and contrast on peripheral grating resolution.
- Curr Eye Res 1995;14:1031-1033.
035
M Birch, S Barbosa, L Blumhardt, C O Brien, S Harding.
- 1996
- Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis.
- Arch Ophthalmol 1996;114-119.
036
RS Ayyala, C O’Brien, I Grierson, P Maltby.
- 1996
- Transcleral flow of aqueous humor: an in-vitro experiment.
- Ophthalmol Surg 1996;27:66-69.
037
J Sing, R Bell, A Adams, C O’Brien,
- 1996
- Enhancement of post trabeculectomy bleb formation by laser suture lysis.
- Br J Ophthalmol 1996;80:624-627.
038
C Lim, C O’Brien, N Bolton.
- 1996
- A simple clinical method to measure the optic disc size in glaucoma.
- J Glaucoma 1996;5:241-245.
039
FD Ghanchi, TH Williamson, CS Lim, Z Butt, GM Baxter, G McKillop, C O’Brien.
- 1996
- Colour Doppler imaging in giant cell (temporal) arteritis: serial examination and comparison with non-arteritic anterior ischaemic optic neuropathy.
- Eye 1996;10:459-464.
040
A Kosmin, M Austin, C.O’Brien, N. Cotu, P. Wishart.
- 1996/1997
- Ageing changes in automated perimetry. A comparison of flicker and luminance sensitivity in normal subjects.
- In: Wall M, Heijl A (eds). Perimetry update 1996/1997. Kugler: Amsterdam, New York 1997, pp 229 - 233.
041
RWD Bell, C O’Brien.
- 1997
- Diagnostic outcome of hospital glaucoma referrals.
- Ophthal Physiol Opt 1997;17:3-6.
042
RWD Bell, C O’Brien.
- 1997
- Accuracy of referral to a glaucoma clinic.
- Ophthal Physiol Opt 1997;17:7-11.
043
C O’Brien, P Kelly, I Ritchie.
- 1997
- The effect of chronic inhibition of nitric oxide synthase on ocular blood flow and glucose metabolism in rats.
- Br J Ophthalmol 1997;81:68-71.
044
Z Butt, C O’Brien, G McKillop, P Aspinall, P Allan.
- 1997
- Colour Doppler imaging in untreated high and normal pressure open angle glaucoma.
- Invest Ophthalmol Vis Sci, 1997; 38: 690-6.
045
C O’Brien, Z Butt, C Ludlum.
- 1997
- Activation of the coagulation cascade in untreated primary open angle glaucoma.
- Ophthalmol 1997; 104:725 - 730
046
RWD Bell, HK Yang, C O’Brien.
- 1997
- A case of bilateral cavernous hemangioma associated with intra-cerebral hemangioma.
- Arch Ophthalmol 1997, 115:6, 818-9.
047
RS Anderson, C O’Brien.
- 1997
- Psychophysical evidence for selective loss of M ganglion cells in glaucoma
- Vis Res 1997 , 37: 1079-1083.
048
RWD Bell, NE Habib, C O’Brien.
- 1997
- Long-term outcome and complications of trabeculectomy with a single per-operative application of 5-fluorouracil.
- Eye 1997;11: 663-71.
049
JR Mackinnon, Z Butt, K Swa, C O’Brien.
- 1997
- Pulsatile ocular blood flow in untreated diabetic retinopathy.
- Acta Ophthalmol, 1997; 75:6, 661-4.
050
C Buckley, P Hadoke, C O’Brien.
- 1997
- The use of isolated ocular arteries in-vitro to define the pathology of vascular changes in glaucoma.
- Br J Ophthalmol 1997, 81:599 - 607
051
C. O’Brien.
- 1998
- Is there a role for computerised image analysis in glaucoma management.
- Br. J Ophthalmol 1998, 82: 2-3. (Editorial).
052
Kerr J, Nelson P, O’Brien C.
- 1998
- A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension.
- Am J Ophthalmol 1998; 126: 42-51.
053
O’Brien C
- 1998
- Vasospasm and glaucoma (Editorial).
- Br J Ophthalmol 1998; 82: 855-6.
054
Kelly PA, Buckley C, Ritchie IM, O’Brien C.
- 1998
- Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat.
- Br J Ophthalmol 1998; 82: 1199-202.
055
Fontana L, Poinoosawmy D, Bunce CV, O’Brien C, Hitchings RA.
- 1998
- Pulsatile ocular blood flow investigation in asymmetric normal-tension glaucoma and normal subjects.
- Br J Ophthalmol 1998; 82: 731-6.
056
Buckley C H, Hadoke P, O’Brien C.
- 1998
- Role of the endothelium in modulating functional responses of isolated bovine anterior ciliary arteries to vasoconstrictor agonists.
- Br J Ophthalmol 1998; 82: 826-829.
057
Edgar DF, Crabb DP, Rudnicka AR, Lawrensen JG, Gutteridge NM, O’Brien C.
- 1999
- Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and Logmar acuity.
- Graefe’s Arch Clin Exp Ophthalmol 1999; 237: 117-24.
058
Nelson P, Aspinall P, O’Brien C.
- 1999
- Patients’ perception of visual impairment in glaucoma. A pilot study.
- Br J Ophthalmol 1999; 83: 546-552.
059
Henry E, Newby DE, Webb DJ, O’Brien C.
- 1999
- Peripheral endothelial dysfunction in normal pressure glaucoma.
- Invest Ophthalmol Vis Sci 1999; 40: 1710-1714.
060
O’Brien C, Butt Z.
- 1999
- Blood flow velocity in the peripheral circulation of glaucoma patients.
- Ophthalmologica 1999; 213: 150-153.
061
J Stokes, E Henry, C O’Brien.
- 1998/1999
- Differential Diagnosis of Normal Tension Glaucoma (1998)
- In: Pillunat L, Harris A (eds) Fortbildurg Glaucoma. Enke Verlag, Stuggart, 1999.
062
King A, Bolton N, Aspinall P, O’Brien C.
- 2000
- Retinal nerve fibre layer volume in glaucoma.
- Am J Ophthalmol 2000, 129: 599-607.
063
Stokes J, Andrew R, Seckyl J, O’Brien C.
- 2000
- Glucocorticoid and mineralocorticoid receptors and 11-beta-deyhydrogenase activity in rat and human ocular tissue.
- Invest Ophthalmol Vis Sci 2000; 41: 1629-38.
064
McKinnon J, McKillop G, Swa K, O’Brien C, Butt Z, Nelson P.
- 2000
- Colour Doppler imaging of the ocular circulation in diabetic retinopathy.
- Acta Ophthalmol, 2000, 78: 386-9.
065
Morgan-Davies J, King A, Aspinall P, O’Brien C.
- 2000
- Measurement of a novel optic disc topographic parameter ‘spikiness’ in glaucoma.
- Graefe’s Arch Clin Exp Ophthalmol 2000, 238: 669- 76.
066
Devlin H, O’Brien C.
- 2001
- Normal tension glaucoma: Diagnosis and Management.
- CME Journal Ophthalmol 2001; 5(1): 13-17.
067
O’Toole L, Cahill M, O’Brien C.
- 2001
- Eyelid hypertrichosis associated with latanoprost is reversible.
- Eur J Ophthalmol. 2001 Oct-Dec;11(4):377-9.
068
Buckley C, Hadoke P, Henry E, O’Brien C.
- 2002
- Systemic vascular endothelial dysfunction in normal pressure glaucoma
- Br J Ophthalmology 2002; 86; 227-32.
069
P Nelson, P Aspinall, C O’Brien.
- 2003
- The relationship between quality of life and visual function in glaucoma.
- J Glaucoma 2003 Apr 12(2) 139-50.
070
S Quinn, C O’Brien, P McLoughlin.
- 2003
- Nitric oxide independent vasorelaxation in the bovine long posterior ciliary artery.
- Eye 2003 July 17(5) 628-36.
071
J Kerr, C O’Brien.
- 2003
- Ocular blood flow in untreated ocular hypertension.
- Am J Ophthalmology 2003 Dec 136(6) 1106-13.
072
J Stokes, R Best, C O’Brien, J Seckl.
- 2003
- Altered glucocorticoid peripheral sensitivity in glaucoma.
- Invest Ophthal Vis Sci 2003; Dec 44(12) 5163-7.
073
R Kirwan, J Crean, C Fenerty, A Clark, C O’Brien.
- 2004
- Effect of cyclical mechanical stretch and exogenous transforming growth factor-B1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
- J Glaucoma 2004 Aug; 13(4): 327-34.
074
Morgan-Davies J, Taylor N, Hill AR, Aspinall P, O’Brien CJ, Asuara-Blanco A.
- 2004
- Three dimensional analysis of the lamina cribrosa in glaucoma.
- Br J Ophthalmol 2004 Oct;88(10): 1299-304.
075
S L Ho, G F Dogar, J Wang, J Crean, Q D Wu, N Oliver, S Weitz, A Murray, P E Cleary, C O’Brien.
- 2005
- Elevated aqueous humour tissue inhibitor of matrix metalloproteinase-1 and connective tissue growth factor in pseudoexfoliation disease.
- Br J Ophthalmol 2005;89:169-173.
076
C Cleary, C H Buckley, E Henry, P McLoughlin, C O’Brien, P W Hadoke.
- 2005
- Enhanced endothelium derived hyperpolarized factor activity in resistance arteries from normal pressure glaucoma patients: implications for vascular function in the eye.
- Br J Ophthalmol 2005;89:223-228
077
T E Walshe, G Ferguson, P Connell, C O’Brien, P A Cahill.
- 2005
- Pulsatile flow increases the expression of eNOS, ET-1, and Prostacyclin in a novel in vitro coculture model of the retinal vasculature.
- Invest Ophthal Vis Sci 2005;Jan(46)1:375-382.
078
P Aspinall, A Hill, P Nelson, C O’Brien, E O’Connell, L McCloughan, A Azuara-Blanco, R Brice, S Green, C Steeds.
- 2005
- Quality of life in patients with glaucoma: a conjoint analysis approach.
- Visual Impairment Research 2005; 7 (1): 13-26.
079
VW Long, C O’Brien.
- 2005
- Trends in ophthalmic surgery in Ireland.
- Irish Journal Med. Sci 2005; 174 (2); 36-39
080
R Kirwan, M O’Leonard, M Murphy A F Clark, C O’Brien
- 2005
- Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells.
- Glia. 2005 Dec;52(4):309-24.
081
R Kirwan, C Fenerty, J Crean, R Wordinger, A F Clark, C O’Brien
- 2005
- Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro.
- Mol Vis 2005 Sep 23;11:798-810
082
R Kane, L Stevenson, C Godson, A Stitt, C O’Brien.
- 2005
- Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose.
- Br J Ophthalmol 2005; Dec;89(12): 1638-42
083
A Knox, M Barry, C O’Brien.
- 2006
- The rising cost of glaucoma drugs in Ireland. 1996-2003.
- Br J Ophthalmol 2006 Feb;90(2):162-5
084
McKernan DP, Caplis C, Donovan M, O’Brien C, Cotter T.
- 2006
- Age-dependent susceptibility of the retinal ganglion cell layer to cell death.
- Invest Ophthalmol Vis Sci. 2006 Mar;47(3):807-14.
085
C Kelliher, D Kenny, C O’Brien.
- 2006
- Trends in blind registration in the adult population of the Republic of Ireland. 1996-2003.
- Br J Ophthalmol 2006 Mar;90(3)367-71.
086
L Cryan, G Pidgeon, D Fitzgerald, C O’Brien.
- 2006
- COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
- Mol Vis. 2006 Apr 20;12:405-14
087
E Henry, D Newby, DJ Webb, PW Hadoke, C O’Brien.
- 2006
- Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma.
- Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2528-32.
088
Y Delaney, T Walshe, C O’Brien.
- 2006
- Vasospasm in glaucoma: clinical and laboratory aspects.
- Optom Vis Sci. 2006 Jul;83(7):406-14.
089
Guerin MB, McKernan DP, O’Brien CJ, Cotter TG.
- 2006
- Retinal ganglion cells: dying to survive.
- Int J Dev Biol. 2006;50(8):665-74..
090
McKernan DP, Guerin MB, O’Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death.
- 2007
- Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5420-30.
091
Lee H, O’Meara SJ, O’Brien C, Kane R.
- 2007
- The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy.
- Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4291-9.
092
Connell P, Walshe T, Ferguson G, Gao W, O’Brien C, Cahill PA.
- 2007
- Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells.
- Endothelium. 2007 Jan-Feb;14(1):17-24.
093
Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O’Brien C, Cahill PA.
- 2007
- High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.
- J Mol Cell Cardiol. 2007 Mar;42(3):609-19. Epub 2006 Dec 21.
094
Horgan N, Kirwan RP, O’Brien CJ.
- 2007
- Choroidal detachment associated with latanoprost use in the fellow eye.
- Ann Pharmacother. 2007 Jan;41(1):161-2.
095
Cryan LM, Paraoan L, Hiscott P, Damato BE, Grierson I, Gray D, Farrell M, Doherty GA, Fitzgerald DJ, O’Brien C.
- 2008
- Expression of COX-2 and prognostic outcome in uveal melanoma.
- Curr Eye Res. 2008 Feb;33(2):177-84.
096
Aragon-Martin JA, Ritch R, Liebmann J, O’Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Damji KF, Tarkkanen A, Rezaie T, Child AH, Sarfarazi M.
- 2008
- Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
- Mol Vis. 2008 Mar 17;14:533-41.
097
O’Driscoll C, O’Connor J, O’Brien CJ, Cotter TG.
- 2008
- Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
- J Neurochem. 2008 Apr;105(2):524-36. Epub 2007 Dec 13.
098
Kane R, Godson C, O’Brien C.
- 2008
- Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
- Mol Vis. 2008 Jun 20;14:1138-48.
099
O’Connor JC, Wallace DM, O’Brien C, Cotter TG. A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- 2008
- A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4237-44
100
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O’Brien C, Walls D, Redmond EM, Cahill PA.
- 2008
- Notch and vascular smooth muscle cell phenotype.
- Circ Res. 2008 Dec 5;103(12):1370-82.
101
Cryan L, O’Brien C.
- 2008
- Proteomics as a research tool in clinical and experimental ophthalmology.
- Proteomics Clin. App. 2008; 2(5); 762-75
102
Guerin M, Flynn T, Brady J, O’Brien C.
- 2008
- Worldwide geographical distribution of ophthalmic publications.
- Int Ophthalmol; 2008; 29: 511-6.
103
Cryan L, Fitzgerald D, O’Brien C.
- 2009
- Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclogenase.
- Prostaglandins, Leuko & Essent Fatty Acids 2009 81:401-9.
104
Irnaten M, Barry RC, Quill B, Clark AF, Harvey BJ, O’Brien CJ.
- 2009
- Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells.
- Invest Ophthalmol Vis Sci. 2009 Jan;50(1):194-202. Epub 2008 Sep 4.
105
Kirwan RP, Wordinger RJ, Clark AF, O’Brien CJ.
- 2009
- Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells.
- Mol Vis. 2009;15:76-88. Epub 2009 Jan 15.
106
Quaranta L, Konstas AG, Rossetti L, Garcia-Feijoo J, O’Brien C, Nasr MB, Fogagnolo P, Demos CM, Stewart JA, Stewart WC.
- 2010
- Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry.
- Eye (Lond). 2010 Jul;24(7):1252-8. Epub 2009 Dec 4.
107
Dervan EW, Chen H, Ho SL, Brummel N, Schmid J, Toomey D, Haralambova M, Gould E, Wallace DM, Prehn JH, O’Brien C, Murphy D.
- 2010
- Protein Macroarray Profiling of Serum Autoantibodies in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2968-75.
108
P O’Connor R, Cryan LM, Wynne K, de Stefani A, Fitzgerald D, O’Brien C, Cagney G.
- 2010
- Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.
- J Biomed Biotechnol. 2010; 2010:107859.
109
Walshe TE, Connell P, Cryan L, Ferguson G, O’Brien C, Cahill PA.
- 2011
- The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation.
- Cardiovasc Res. 2011 Feb 15;89(3):661-70.
110
Farrell SM, Groeger G, Bhatt L, Finnegan S, O’Brien CJ, Cotter TG.
- 2011
- bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.
- Eur J Neurosci. 2011 Feb;33(4):632-41.
111
Quill B, Docherty N, Clark AF, O’Brien CJ.
- 2011
- The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
112
Guerin M, Cotter T, McKernan D, O’Brien C.
- 2011
- Age Dependent Rat Retinal Ganglion Cell Susceptibility to Apoptotic Stimuli: Implications for Glaucoma.
- Clin & Exper Ophthalmol Apr;39(3):243-51. 2011
113
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O’Brien CJ, Wallace DM
- 2011
- Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.
- Mol Vis. 2011;17:1182-91.
114
Gallagher BA, Hart PM, O’Brien C, Stevenson MR, Jackson AJ.
- 2011
- Mobility and access to transport issues as experienced by people with vision impairment living in urban and rural Ireland.
- Disabil Rehabil. 2011;33(12):979-88.
115
Browne JG, Ho SL, Kane R, Oliver N, Clark AF, O’Brien CJ, Crean JK.
- 2011
- Connective Tissue Growth Factor is increased in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3660-6
116
Walshe TE, Connell P, Cryan L, Ferguson G, Gardiner T, Morrow D, Redmond EM, O’Brien C, Cahill PA
- 2011
- Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch signaling.
- Invest Ophthalmol Vis Sci. 2011 . Jun 23;52(7):4472-83.
117
Wiggs JL, Hewitt AW, Fan BJ, Wang DY, Figueiredo Sena DR, O’Brien C, Realini A, Craig JE, Dimasi DP, Mackey DA, Haines JL, Pasquale LR.
- 2012
- The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.
- PLoS One. 2012;7(9):e45613. doi: 10.1371/journal.pone.0045613. Epub 2012 Sep 26
118
Kirwan RP, Felice L, Clark AF, O’Brien CJ, Leonard MO.
- 2012
- Hypoxia regulated gene transcription in human optic nerve lamina cribrosa cells in culture.
- Invest Ophthalmol Vis Sci. 2012 53:2243-2255
119
Bhattacharya SK, Lee RK, Grus FH;
- 2013
- Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group. Molecular biomarkers in glaucoma.
- 2013 Jan 7;54(1):121-31
120
Igras E, Loughman J, Ratzlaff M, O’Caoimh R, O’Brien C.
- 2013
- Evidence of lower macular pigment optical density in chronic open angle glaucoma. Br J Ophthalmol. 2013 Aug;97(8):994-998
- Br J Ophthalmol. 2013 Aug;97(8):994-998
121
Irnaten M, Barry RC, Wallace DM, Docherty NG, Quill B, Clark AF, O’Brien CJ.
- 2013
- Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells
- Exp Eye Res 2013 Oct; 115:224-9
122
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .
- 2013
- Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.
- Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
123
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ
- 2014
- The role of matricellular proteins in glaucoma.
- Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4
124
McDonnell F, O’Brien C, Wallace D.
- 2014
- The role of epigenetics in the fibrotic processes associated with glaucoma.
- J Ophthalmol. 2014~:750459.
125
Gao W, Ferguson G, Connell P, Walshe T, O’Brien C, Redmond EM, Cahill PA.
- 2014
- Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression.
- Diab Vasc Dis Res. 2014 May 22;11(4):270-280.
126
Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O’Brien C, McKnight AJ, Willoughby CE
- 2014
- Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.
- Genet Med. 2014 Sep 18.
127
McNally S, O’Brien CJ. Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
- 2014
- Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma.
- J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
128
McElnea EM, Hughes E, McGoldrick A, McCann A, Quill B, Docherty N, Irnaten M, Farrell M, Clark AF, O’Brien CJ, Wallace DM.
- 2014
- Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells.
- BMC Ophthalmol. 2014 Dec 2;14:153.
129
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O’Brien CJ
- 2015
- ‘Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cells’.
- Br J Ophthalmol. 2015 Mar 20. pii: bjophthalmol-2014-306093. doi: 10.1136/bjophthalmol-2014-306093. [Epub ahead of print]
130
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The function of matricellular proteins in the lamina cribrosa and trabecular meshwork in glaucoma.
- J Ocul Pharmacol Ther. 2015 Apr 7. [Epub ahead of print]
131
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR
- 2015
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2015 Apr 21. [Epub ahead of print]
132
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95.
133
Siah WF, Loughman J, O’Brien C.
- 2015
- Lower Macular Pigment Optical Density in Foveal-Involved Glaucoma.
- Ophthalmology. 2015 Oct;122(10):2029-37.
134
Quill B, Henry E, Simon E, O’Brien CJ.
- 2015
- Evaluation of the Effect of Hypercapnia on Vascular Function in Normal Tension Glaucoma.
- Biomed Res Int. 2015;2015:418159.
135
Wallace DM, O’Brien CJ. The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- 2016
- The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- Exp Eye Res. 2016 Jan;142:102-9.
136
O’Brien C, Clark AF.
- 2016
- Introduction to EER Special Issue on ocular fibrosis.
- Exp Eye Res. 2016 Jan;142:1.
137
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR.
- 2016
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2016 Feb;25(2):e99-e105.
138
Pokrovskaya O, O’Brien C.
- 2016
- What's in a Gene? Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient.
- Case Rep Ophthalmol. 2016 Jan 21;7(1):54-60. doi: 10.1159/000443697. eCollection 2016 Jan 21.
139
McDonnell F, Irnaten M, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.
- PLoS One. 2016 Apr 28;11(4):e0153354. doi: 10.1371/journal.pone.0153354. eCollection 2016 Apr 28.
140
Treacy MP, O’Neill EC, Murphy M, O’Toole L, Delaney Y, O’Brien C, Connell PP.
- 2016
- Opportunistic detection of glaucomatous optic discs within a diabetic retinopathy screening service.
- Eur J Ophthalmol. 2016 Jun 10;26(4):315-20. doi: 10.5301/ejo.5000722. Epub 2015 Dec 17.
141
Paula JS, O’Brien C, Stamer WD.
- 2016
- Life under pressure: The role of ocular cribriform cells in preventing glaucoma.
- Exp Eye Res. 2016 Oct;151:150-9. doi: 10.1016/j.exer.2016.08.014. Epub 2016 Aug 25. Review.
142
McDonnell FS, McNally SA, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells.
- J Glaucoma. 2016 Oct;25(10):e834-e842.
143
Murphy ML, Pokrovskaya O, Galligan M, O’Brien C.
- 2017
- Corneal hysteresis in patients with glaucoma-like optic discs, ocular hypertension and glaucoma.
- BMC Ophthalmol. 2017 Jan 10;17(1):1. doi: 10.1186/s12886-016-0396-9.
144
O’Callaghan J, Crosbie DE, Cassidy PS, Sherwood JM, Flügel-Koch C, Lütjen-Drecoll E, Humphries MM, Reina-Torres E, Wallace D, Kiang AS, Campbell M, Daniel SW, Overby DR, O’Brien C, Tam LC, Humphries P.
- 2017
- Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.
- Hum Mol Genet. 2017 Feb 1. doi: 10.1093/hmg/ddx028.
145
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95. doi: 10.1089/jop.2014.0163. Epub 2015 Apr 7. Review.
146
Barrett C, O’Brien C, Butler JS, Loughman J.
- 2017
- Barriers to glaucoma case finding as perceived by optometrists in Ireland.
- Clin Exp Optom. 2017 Jul 17. doi: 10.1111/cxo.12573.
147
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O’Brien CJ.
- 2017
- Aging and ocular tissue stiffness in glaucoma.
- Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
148
Kamel K, Farrell M, O’Brien C.
- 2017
- Mitochondrial dysfunction in ocular disease: Focus on glaucoma.
- Mitochondrion. 2017 Jul;35:44-53. doi: 10.1016/j.mito.2017.05.004. Epub 2017 May 9.
149
Siah WF, O’Brien C, Loughman JJ.
- 2017
- Macular pigment is associated with glare-affected visual function and central visual field loss in glaucoma.
- Br J Ophthalmol. 2017 Oct 5. pii: bjophthalmol-2017-310215. doi: 10.1136/bjophthalmol-2017-310215. [Epub ahead of print]
150
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O’Brien CJ.
- 2018
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi: 1
151
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O’Brien C.
- 2018
- Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi: 10.1167/iovs.17-22531.
152
Barrett C, O’Brien C, Loughman J.
- 2018
- Glaucoma referral refinement in Ireland: managing the sensitivity-specificity paradox in optometric practice.
- Ophthalmic Physiol Opt. 2018 Feb 28. doi: 10.1111/opo.12446
153
Kamel K, Falzan K, Dervan E, O’Brien C.
- 2018
- Difference in intraocular pressure measurements between non-contact tonometry and Goldman applanation tonometry
- Ir J Med Sci. 2018
154
Kamel K, Bourke L, O’Brien C.
- 2018
- Clinical and Laboratory Biomarkers for Pseudoexfoliation Syndrome.
- J Glaucoma. 2018 Jul;27 Suppl 1:S111-S113.
155
Loskutova E, O’Brien C, Loskutov I, Loughman J.
- 2018
- Nutritional supplementation in the treatment of glaucoma: A systematic review.
- Surv Ophthalmol. 2018 Oct 6. pii: S0039-6257(18)30100-0.
156
Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, Kennedy C, Clerkin S, Doyle B, Godson C, Connell P, O’Brien C, Cagney G, Crean J.
- 2019
- Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.
- FASEB J. 2019 May;33(5):6667-6681. doi: 10.1096/fj.201800566RR
157
Bourke CM, Loughman J, Fltcroft DI, Loskutova E, O’Brien C.
- 2019
- We can't afford to turn a blind eye to myopia.
- QJM. 2019 Mar 26. pii: hcz076. doi: 10.1093/qjmed/hcz076.
158
Murtagh P, Greene G, O’Brien C.
- 2020
- Current application of machine learning in the screening and diagnosis of glaucoma: a systematic review and Meta-analysis.
- Int J Ophthalmic. 2020 Jan18;13(1):149-162
159
Greene AG, Eivers SB, Dervan EWJ,O’Brien CJ, Wallace DM.
- 2020
- Lysyl Oxidase Like 1: Biological roles and regulation.
- Exp Eye Res. 2020 Apr;193107975. doi:10.1016/j.exer.2020.107975. Epub 2020 Feb15.
160
Iraten M, O’Malley G, Clark AF, O’Brien CJ.
- 2020
- Transient receptor potential channels TRPC1/TRPC6 regulate lamina cribrosa cell extracellular matrix gene transcription and proliferation.
- Exp Eye Res. 2020 Apr;193:107980. doi: 10.1016/j.exer.2020.107980. Epub 2020 Feb 20.
161
Eivers SB, Greene AG, Dervan E, O’Brien C, Wallace D
- 2020
- Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants Within Lysyl Oxidase-like 1 in an Irish Population.
- J Glaucoma. 2020 Jun;29(6):417-422. doi:10.1097/IJG.0000000000001475.
162
Rahman N, O’Neill E, Irnaten M, Wallace D, O’Brien C.
- 2020
- Corneal Stiffness and Collagen Cross-Linking Proteins in Glaucoma: Potential for Novel Therapeutic Strategy.
- J Ocul Pharmacol Ther. 2020 Jul 13. doi: 10.1089/jop.2019.0118.
163
Hopkins AA, Murphy R, Irnaten M, Wallace DM, Quill B, O’Brien C.
- 2020
- The Role of Lamina Cribrosa Tissue Stiffness and Fibrosis as Fundamental Biomechanical Drivers of Pathological Glaucomatous Cupping.
- Am J Physiol Cell Physiol. 2020 Jul 15. doi: 10.1152/ajpcell.00054.2020.
164
Kamel K, O’Brien CJ, Zhdanov AV, Papkovsky DB, Clark AF, Stamer WD, Irnaten M.
- 2020
- Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):4. doi: 10.1167/iovs.61.13.4.
165
Irnaten M, Duff A, Clark A, O’Brien C.
- 2020
- Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.
- J Clin Med. 2020 Dec 26;10(1):62. doi: 10.3390/jcm10010062.
166
Greene AG, Eivers SB, McDonnell F, Dervan EWJ, O’Brien CJ, Wallace DM.
- 2020
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation.
- Exp Eye Res. 2020 Dec;201:108349. doi: 10.1016/j.exer.2020.108349. Epub 2020
167
Cassidy PS, Kelly RA, Reina-Torres E, Sherwood JM, Humphries MM, Kiang AS, Farrar GJ, O’Brien C, Campbell M, Stamer WD, Overby DR, Humphries P, O’Callaghan J.
- 2020
- siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.
- Mol Ther Methods Clin Dev. 2020 Oct 31;20:86-94. doi: 10.1016/j.omtm.2020.10.022. eCollection 2021 Mar 12.
168
Kamel K, Dervan E, Falzon K, O’Brien C.
- 2020
- Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals.
- Ir J Med Sci. 2019 Feb;188(1):321-325. doi: 10.1007/s11845-018-1795-0. Epub 2018 Apr 4.
169
Doolan E, O’Brien C.
- 2021
- Abnormal corneal properties in osteogenesis imperfect and glaucoma: a case series.
- BMJ Open Ophthalmic. 2021 Apr15;6(1):e000684 doi: 10.1136/bmjophth-2020-000684. eCollection 2021.
170
O’Regan A, O’Brien CJ, Eivers SB.
- 2021
- The lysophosphatidic acid axis in fibrosis: Implications for glaucoma.
- Wound Repair Regen. 2021 Jul;29(4):613-626. doi: 10.1111/wrr.12929. Epub 2021 May 19.
171
Hurley DJ, Iranaten, O’Brien C.
- 2021
- Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics.
- Cells 2021 Aug 19;10(8):2131. Doi: 10.3390/cells10082131.
172
Kelly RA, Perkumas KM, Campbell M, Farrar GJ, Stamer WD, Humphries P, O’Callaghan J, O’Brien CJ.
- 2021
- Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma.
- Int J Mol Sci. 2021 Aug 31;22(17):9446. Doi 10.3390/ijms22179446.
173
Murphy R, Irnaten M, Hopkins A, O Callaghan J, Stamer WD, Clark AF, Wallace D, O’Brien CJ.
- 2022
- Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):16 doi: 10.1167/iovs.63.1.16.
174
Powell S, Doolan E, Curtin K, Doyle A, O’Brien C.
- 2022
- Audit of outcomes following attendance at the City West drive-through IOP glaucoma clinic during COVID-19 pandemic.
- Ir J Med Sci. 2022 Jan 16:1-10. doi: 10.1007/s11845-021-02893-9.
175
Powell S, Irnaten M, O’Brien C.
- 2022
- Glaucoma – A Stiff Eye in a Stiff Body
- Curr Eye Res. 2022 Mar 7:1-9. doi: 10.1080/02713683.2022.2039204.
176
Hurley DJ, Normile C, Irnaten M, O’Brien C.
- 2022
- The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma.
- Antioxidants (Basel). 2022 Apr 29;11(5):886. doi: 10.3390/antiox11050886
177
Murtagh P, O’Brien C.
- 2022
- Corneal Hysteresis, Intraocular Pressure and Progression of Glaucoma: Time for a “Hyst-Oric” Change in Clinical Practice?
- J Clin Med. 2022 May 20;11(10):2895. doi: 10.3390/jcm11102895
178
P Murtagh, S Neary, C.J O’Brien
- 2022
- Screening for Glaucoma in Adults: Our Vision
- Ir MedJ 2022 Sept 15; 115(8):646
179
Symth A, Callaghan B, Willoughby CE, C.J O’Brien
- 2022
- The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy
- Int J Mol Sci. 2022 Sep 6:23(18):10216. doi:10.3390/ijms
180
Imaten M, C.J.O’Brien
- 2023
- Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts.
- Int J Mol Sci. 2023 Jan 9;24(2):1287. doi 10.3390/jmis24021287
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180
Imaten M, C.J.O’Brien
- 2023
- Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts.
- Int J Mol Sci. 2023 Jan 9;24(2):1287. doi 10.3390/jmis24021287
179
Symth A, Callaghan B, Willoughby CE, C.J O’Brien
- 2022
- The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy
- Int J Mol Sci. 2022 Sep 6:23(18):10216. doi:10.3390/ijms
178
P Murtagh, S Neary, C.J O’Brien
- 2022
- Screening for Glaucoma in Adults: Our Vision
- Ir MedJ 2022 Sept 15; 115(8):646
177
Murtagh P, O’Brien C.
- 2022
- Corneal Hysteresis, Intraocular Pressure and Progression of Glaucoma: Time for a “Hyst-Oric” Change in Clinical Practice?
- J Clin Med. 2022 May 20;11(10):2895. doi: 10.3390/jcm11102895
176
Hurley DJ, Normile C, Irnaten M, O’Brien C.
- 2022
- The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma.
- Antioxidants (Basel). 2022 Apr 29;11(5):886. doi: 10.3390/antiox11050886
175
Powell S, Irnaten M, O’Brien C.
- 2022
- Glaucoma – A Stiff Eye in a Stiff Body
- Curr Eye Res. 2022 Mar 7:1-9. doi: 10.1080/02713683.2022.2039204.
174
Powell S, Doolan E, Curtin K, Doyle A, O’Brien C.
- 2022
- Audit of outcomes following attendance at the City West drive-through IOP glaucoma clinic during COVID-19 pandemic.
- Ir J Med Sci. 2022 Jan 16:1-10. doi: 10.1007/s11845-021-02893-9.
173
Murphy R, Irnaten M, Hopkins A, O Callaghan J, Stamer WD, Clark AF, Wallace D, O’Brien CJ.
- 2022
- Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):16 doi: 10.1167/iovs.63.1.16.
172
Kelly RA, Perkumas KM, Campbell M, Farrar GJ, Stamer WD, Humphries P, O’Callaghan J, O’Brien CJ.
- 2021
- Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma.
- Int J Mol Sci. 2021 Aug 31;22(17):9446. Doi 10.3390/ijms22179446.
171
Hurley DJ, Iranaten, O’Brien C.
- 2021
- Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics.
- Cells 2021 Aug 19;10(8):2131. Doi: 10.3390/cells10082131.
170
O’Regan A, O’Brien CJ, Eivers SB.
- 2021
- The lysophosphatidic acid axis in fibrosis: Implications for glaucoma.
- Wound Repair Regen. 2021 Jul;29(4):613-626. doi: 10.1111/wrr.12929. Epub 2021 May 19.
169
Doolan E, O’Brien C.
- 2021
- Abnormal corneal properties in osteogenesis imperfect and glaucoma: a case series.
- BMJ Open Ophthalmic. 2021 Apr15;6(1):e000684 doi: 10.1136/bmjophth-2020-000684. eCollection 2021.
168
Kamel K, Dervan E, Falzon K, O’Brien C.
- 2020
- Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals.
- Ir J Med Sci. 2019 Feb;188(1):321-325. doi: 10.1007/s11845-018-1795-0. Epub 2018 Apr 4.
167
Cassidy PS, Kelly RA, Reina-Torres E, Sherwood JM, Humphries MM, Kiang AS, Farrar GJ, O’Brien C, Campbell M, Stamer WD, Overby DR, Humphries P, O’Callaghan J.
- 2020
- siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.
- Mol Ther Methods Clin Dev. 2020 Oct 31;20:86-94. doi: 10.1016/j.omtm.2020.10.022. eCollection 2021 Mar 12.
166
Greene AG, Eivers SB, McDonnell F, Dervan EWJ, O’Brien CJ, Wallace DM.
- 2020
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation.
- Exp Eye Res. 2020 Dec;201:108349. doi: 10.1016/j.exer.2020.108349. Epub 2020
165
Irnaten M, Duff A, Clark A, O’Brien C.
- 2020
- Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.
- J Clin Med. 2020 Dec 26;10(1):62. doi: 10.3390/jcm10010062.
164
Kamel K, O’Brien CJ, Zhdanov AV, Papkovsky DB, Clark AF, Stamer WD, Irnaten M.
- 2020
- Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):4. doi: 10.1167/iovs.61.13.4.
163
Hopkins AA, Murphy R, Irnaten M, Wallace DM, Quill B, O’Brien C.
- 2020
- The Role of Lamina Cribrosa Tissue Stiffness and Fibrosis as Fundamental Biomechanical Drivers of Pathological Glaucomatous Cupping.
- Am J Physiol Cell Physiol. 2020 Jul 15. doi: 10.1152/ajpcell.00054.2020.
162
Rahman N, O’Neill E, Irnaten M, Wallace D, O’Brien C.
- 2020
- Corneal Stiffness and Collagen Cross-Linking Proteins in Glaucoma: Potential for Novel Therapeutic Strategy.
- J Ocul Pharmacol Ther. 2020 Jul 13. doi: 10.1089/jop.2019.0118.
161
Eivers SB, Greene AG, Dervan E, O’Brien C, Wallace D
- 2020
- Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants Within Lysyl Oxidase-like 1 in an Irish Population.
- J Glaucoma. 2020 Jun;29(6):417-422. doi:10.1097/IJG.0000000000001475.
160
Iraten M, O’Malley G, Clark AF, O’Brien CJ.
- 2020
- Transient receptor potential channels TRPC1/TRPC6 regulate lamina cribrosa cell extracellular matrix gene transcription and proliferation.
- Exp Eye Res. 2020 Apr;193:107980. doi: 10.1016/j.exer.2020.107980. Epub 2020 Feb 20.
159
Greene AG, Eivers SB, Dervan EWJ,O’Brien CJ, Wallace DM.
- 2020
- Lysyl Oxidase Like 1: Biological roles and regulation.
- Exp Eye Res. 2020 Apr;193107975. doi:10.1016/j.exer.2020.107975. Epub 2020 Feb15.
158
Murtagh P, Greene G, O’Brien C.
- 2020
- Current application of machine learning in the screening and diagnosis of glaucoma: a systematic review and Meta-analysis.
- Int J Ophthalmic. 2020 Jan18;13(1):149-162
157
Bourke CM, Loughman J, Fltcroft DI, Loskutova E, O’Brien C.
- 2019
- We can't afford to turn a blind eye to myopia.
- QJM. 2019 Mar 26. pii: hcz076. doi: 10.1093/qjmed/hcz076.
156
Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, Kennedy C, Clerkin S, Doyle B, Godson C, Connell P, O’Brien C, Cagney G, Crean J.
- 2019
- Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.
- FASEB J. 2019 May;33(5):6667-6681. doi: 10.1096/fj.201800566RR
155
Loskutova E, O’Brien C, Loskutov I, Loughman J.
- 2018
- Nutritional supplementation in the treatment of glaucoma: A systematic review.
- Surv Ophthalmol. 2018 Oct 6. pii: S0039-6257(18)30100-0.
154
Kamel K, Bourke L, O’Brien C.
- 2018
- Clinical and Laboratory Biomarkers for Pseudoexfoliation Syndrome.
- J Glaucoma. 2018 Jul;27 Suppl 1:S111-S113.
153
Kamel K, Falzan K, Dervan E, O’Brien C.
- 2018
- Difference in intraocular pressure measurements between non-contact tonometry and Goldman applanation tonometry
- Ir J Med Sci. 2018
152
Barrett C, O’Brien C, Loughman J.
- 2018
- Glaucoma referral refinement in Ireland: managing the sensitivity-specificity paradox in optometric practice.
- Ophthalmic Physiol Opt. 2018 Feb 28. doi: 10.1111/opo.12446
151
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O’Brien C.
- 2018
- Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi: 10.1167/iovs.17-22531.
150
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O’Brien CJ.
- 2018
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi: 1
149
Siah WF, O’Brien C, Loughman JJ.
- 2017
- Macular pigment is associated with glare-affected visual function and central visual field loss in glaucoma.
- Br J Ophthalmol. 2017 Oct 5. pii: bjophthalmol-2017-310215. doi: 10.1136/bjophthalmol-2017-310215. [Epub ahead of print]
148
Kamel K, Farrell M, O’Brien C.
- 2017
- Mitochondrial dysfunction in ocular disease: Focus on glaucoma.
- Mitochondrion. 2017 Jul;35:44-53. doi: 10.1016/j.mito.2017.05.004. Epub 2017 May 9.
147
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O’Brien CJ.
- 2017
- Aging and ocular tissue stiffness in glaucoma.
- Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
146
Barrett C, O’Brien C, Butler JS, Loughman J.
- 2017
- Barriers to glaucoma case finding as perceived by optometrists in Ireland.
- Clin Exp Optom. 2017 Jul 17. doi: 10.1111/cxo.12573.
145
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95. doi: 10.1089/jop.2014.0163. Epub 2015 Apr 7. Review.
144
O’Callaghan J, Crosbie DE, Cassidy PS, Sherwood JM, Flügel-Koch C, Lütjen-Drecoll E, Humphries MM, Reina-Torres E, Wallace D, Kiang AS, Campbell M, Daniel SW, Overby DR, O’Brien C, Tam LC, Humphries P.
- 2017
- Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.
- Hum Mol Genet. 2017 Feb 1. doi: 10.1093/hmg/ddx028.
143
Murphy ML, Pokrovskaya O, Galligan M, O’Brien C.
- 2017
- Corneal hysteresis in patients with glaucoma-like optic discs, ocular hypertension and glaucoma.
- BMC Ophthalmol. 2017 Jan 10;17(1):1. doi: 10.1186/s12886-016-0396-9.
142
McDonnell FS, McNally SA, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells.
- J Glaucoma. 2016 Oct;25(10):e834-e842.
141
Paula JS, O’Brien C, Stamer WD.
- 2016
- Life under pressure: The role of ocular cribriform cells in preventing glaucoma.
- Exp Eye Res. 2016 Oct;151:150-9. doi: 10.1016/j.exer.2016.08.014. Epub 2016 Aug 25. Review.
140
Treacy MP, O’Neill EC, Murphy M, O’Toole L, Delaney Y, O’Brien C, Connell PP.
- 2016
- Opportunistic detection of glaucomatous optic discs within a diabetic retinopathy screening service.
- Eur J Ophthalmol. 2016 Jun 10;26(4):315-20. doi: 10.5301/ejo.5000722. Epub 2015 Dec 17.
139
McDonnell F, Irnaten M, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.
- PLoS One. 2016 Apr 28;11(4):e0153354. doi: 10.1371/journal.pone.0153354. eCollection 2016 Apr 28.
138
Pokrovskaya O, O’Brien C.
- 2016
- What's in a Gene? Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient.
- Case Rep Ophthalmol. 2016 Jan 21;7(1):54-60. doi: 10.1159/000443697. eCollection 2016 Jan 21.
137
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR.
- 2016
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2016 Feb;25(2):e99-e105.
136
O’Brien C, Clark AF.
- 2016
- Introduction to EER Special Issue on ocular fibrosis.
- Exp Eye Res. 2016 Jan;142:1.
135
Wallace DM, O’Brien CJ. The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- 2016
- The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- Exp Eye Res. 2016 Jan;142:102-9.
134
Quill B, Henry E, Simon E, O’Brien CJ.
- 2015
- Evaluation of the Effect of Hypercapnia on Vascular Function in Normal Tension Glaucoma.
- Biomed Res Int. 2015;2015:418159.
133
Siah WF, Loughman J, O’Brien C.
- 2015
- Lower Macular Pigment Optical Density in Foveal-Involved Glaucoma.
- Ophthalmology. 2015 Oct;122(10):2029-37.
132
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95.
131
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR
- 2015
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2015 Apr 21. [Epub ahead of print]
130
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The function of matricellular proteins in the lamina cribrosa and trabecular meshwork in glaucoma.
- J Ocul Pharmacol Ther. 2015 Apr 7. [Epub ahead of print]
129
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O’Brien CJ
- 2015
- ‘Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cells’.
- Br J Ophthalmol. 2015 Mar 20. pii: bjophthalmol-2014-306093. doi: 10.1136/bjophthalmol-2014-306093. [Epub ahead of print]
128
McElnea EM, Hughes E, McGoldrick A, McCann A, Quill B, Docherty N, Irnaten M, Farrell M, Clark AF, O’Brien CJ, Wallace DM.
- 2014
- Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells.
- BMC Ophthalmol. 2014 Dec 2;14:153.
127
McNally S, O’Brien CJ. Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
- 2014
- Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma.
- J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
126
Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O’Brien C, McKnight AJ, Willoughby CE
- 2014
- Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.
- Genet Med. 2014 Sep 18.
125
Gao W, Ferguson G, Connell P, Walshe T, O’Brien C, Redmond EM, Cahill PA.
- 2014
- Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression.
- Diab Vasc Dis Res. 2014 May 22;11(4):270-280.
124
McDonnell F, O’Brien C, Wallace D.
- 2014
- The role of epigenetics in the fibrotic processes associated with glaucoma.
- J Ophthalmol. 2014~:750459.
123
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ
- 2014
- The role of matricellular proteins in glaucoma.
- Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4
122
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .
- 2013
- Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.
- Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
121
Irnaten M, Barry RC, Wallace DM, Docherty NG, Quill B, Clark AF, O’Brien CJ.
- 2013
- Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells
- Exp Eye Res 2013 Oct; 115:224-9
120
Igras E, Loughman J, Ratzlaff M, O’Caoimh R, O’Brien C.
- 2013
- Evidence of lower macular pigment optical density in chronic open angle glaucoma. Br J Ophthalmol. 2013 Aug;97(8):994-998
- Br J Ophthalmol. 2013 Aug;97(8):994-998
119
Bhattacharya SK, Lee RK, Grus FH;
- 2013
- Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group. Molecular biomarkers in glaucoma.
- 2013 Jan 7;54(1):121-31
118
Kirwan RP, Felice L, Clark AF, O’Brien CJ, Leonard MO.
- 2012
- Hypoxia regulated gene transcription in human optic nerve lamina cribrosa cells in culture.
- Invest Ophthalmol Vis Sci. 2012 53:2243-2255
117
Wiggs JL, Hewitt AW, Fan BJ, Wang DY, Figueiredo Sena DR, O’Brien C, Realini A, Craig JE, Dimasi DP, Mackey DA, Haines JL, Pasquale LR.
- 2012
- The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.
- PLoS One. 2012;7(9):e45613. doi: 10.1371/journal.pone.0045613. Epub 2012 Sep 26
116
Walshe TE, Connell P, Cryan L, Ferguson G, Gardiner T, Morrow D, Redmond EM, O’Brien C, Cahill PA
- 2011
- Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch signaling.
- Invest Ophthalmol Vis Sci. 2011 . Jun 23;52(7):4472-83.
115
Browne JG, Ho SL, Kane R, Oliver N, Clark AF, O’Brien CJ, Crean JK.
- 2011
- Connective Tissue Growth Factor is increased in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3660-6
114
Gallagher BA, Hart PM, O’Brien C, Stevenson MR, Jackson AJ.
- 2011
- Mobility and access to transport issues as experienced by people with vision impairment living in urban and rural Ireland.
- Disabil Rehabil. 2011;33(12):979-88.
113
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O’Brien CJ, Wallace DM
- 2011
- Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.
- Mol Vis. 2011;17:1182-91.
112
Guerin M, Cotter T, McKernan D, O’Brien C.
- 2011
- Age Dependent Rat Retinal Ganglion Cell Susceptibility to Apoptotic Stimuli: Implications for Glaucoma.
- Clin & Exper Ophthalmol Apr;39(3):243-51. 2011
111
Quill B, Docherty N, Clark AF, O’Brien CJ.
- 2011
- The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
110
Farrell SM, Groeger G, Bhatt L, Finnegan S, O’Brien CJ, Cotter TG.
- 2011
- bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.
- Eur J Neurosci. 2011 Feb;33(4):632-41.
109
Walshe TE, Connell P, Cryan L, Ferguson G, O’Brien C, Cahill PA.
- 2011
- The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation.
- Cardiovasc Res. 2011 Feb 15;89(3):661-70.
108
P O’Connor R, Cryan LM, Wynne K, de Stefani A, Fitzgerald D, O’Brien C, Cagney G.
- 2010
- Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.
- J Biomed Biotechnol. 2010; 2010:107859.
107
Dervan EW, Chen H, Ho SL, Brummel N, Schmid J, Toomey D, Haralambova M, Gould E, Wallace DM, Prehn JH, O’Brien C, Murphy D.
- 2010
- Protein Macroarray Profiling of Serum Autoantibodies in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2968-75.
106
Quaranta L, Konstas AG, Rossetti L, Garcia-Feijoo J, O’Brien C, Nasr MB, Fogagnolo P, Demos CM, Stewart JA, Stewart WC.
- 2010
- Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry.
- Eye (Lond). 2010 Jul;24(7):1252-8. Epub 2009 Dec 4.
105
Kirwan RP, Wordinger RJ, Clark AF, O’Brien CJ.
- 2009
- Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells.
- Mol Vis. 2009;15:76-88. Epub 2009 Jan 15.
104
Irnaten M, Barry RC, Quill B, Clark AF, Harvey BJ, O’Brien CJ.
- 2009
- Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells.
- Invest Ophthalmol Vis Sci. 2009 Jan;50(1):194-202. Epub 2008 Sep 4.
103
Cryan L, Fitzgerald D, O’Brien C.
- 2009
- Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclogenase.
- Prostaglandins, Leuko & Essent Fatty Acids 2009 81:401-9.
102
Guerin M, Flynn T, Brady J, O’Brien C.
- 2008
- Worldwide geographical distribution of ophthalmic publications.
- Int Ophthalmol; 2008; 29: 511-6.
101
Cryan L, O’Brien C.
- 2008
- Proteomics as a research tool in clinical and experimental ophthalmology.
- Proteomics Clin. App. 2008; 2(5); 762-75
100
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O’Brien C, Walls D, Redmond EM, Cahill PA.
- 2008
- Notch and vascular smooth muscle cell phenotype.
- Circ Res. 2008 Dec 5;103(12):1370-82.
099
O’Connor JC, Wallace DM, O’Brien C, Cotter TG. A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- 2008
- A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4237-44
098
Kane R, Godson C, O’Brien C.
- 2008
- Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
- Mol Vis. 2008 Jun 20;14:1138-48.
097
O’Driscoll C, O’Connor J, O’Brien CJ, Cotter TG.
- 2008
- Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
- J Neurochem. 2008 Apr;105(2):524-36. Epub 2007 Dec 13.
096
Aragon-Martin JA, Ritch R, Liebmann J, O’Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Damji KF, Tarkkanen A, Rezaie T, Child AH, Sarfarazi M.
- 2008
- Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
- Mol Vis. 2008 Mar 17;14:533-41.
095
Cryan LM, Paraoan L, Hiscott P, Damato BE, Grierson I, Gray D, Farrell M, Doherty GA, Fitzgerald DJ, O’Brien C.
- 2008
- Expression of COX-2 and prognostic outcome in uveal melanoma.
- Curr Eye Res. 2008 Feb;33(2):177-84.
094
Horgan N, Kirwan RP, O’Brien CJ.
- 2007
- Choroidal detachment associated with latanoprost use in the fellow eye.
- Ann Pharmacother. 2007 Jan;41(1):161-2.
093
Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O’Brien C, Cahill PA.
- 2007
- High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.
- J Mol Cell Cardiol. 2007 Mar;42(3):609-19. Epub 2006 Dec 21.
092
Connell P, Walshe T, Ferguson G, Gao W, O’Brien C, Cahill PA.
- 2007
- Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells.
- Endothelium. 2007 Jan-Feb;14(1):17-24.
091
Lee H, O’Meara SJ, O’Brien C, Kane R.
- 2007
- The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy.
- Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4291-9.
090
McKernan DP, Guerin MB, O’Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death.
- 2007
- Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5420-30.
089
Guerin MB, McKernan DP, O’Brien CJ, Cotter TG.
- 2006
- Retinal ganglion cells: dying to survive.
- Int J Dev Biol. 2006;50(8):665-74..
088
Y Delaney, T Walshe, C O’Brien.
- 2006
- Vasospasm in glaucoma: clinical and laboratory aspects.
- Optom Vis Sci. 2006 Jul;83(7):406-14.
087
E Henry, D Newby, DJ Webb, PW Hadoke, C O’Brien.
- 2006
- Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma.
- Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2528-32.
086
L Cryan, G Pidgeon, D Fitzgerald, C O’Brien.
- 2006
- COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
- Mol Vis. 2006 Apr 20;12:405-14
085
C Kelliher, D Kenny, C O’Brien.
- 2006
- Trends in blind registration in the adult population of the Republic of Ireland. 1996-2003.
- Br J Ophthalmol 2006 Mar;90(3)367-71.
084
McKernan DP, Caplis C, Donovan M, O’Brien C, Cotter T.
- 2006
- Age-dependent susceptibility of the retinal ganglion cell layer to cell death.
- Invest Ophthalmol Vis Sci. 2006 Mar;47(3):807-14.
083
A Knox, M Barry, C O’Brien.
- 2006
- The rising cost of glaucoma drugs in Ireland. 1996-2003.
- Br J Ophthalmol 2006 Feb;90(2):162-5
082
R Kane, L Stevenson, C Godson, A Stitt, C O’Brien.
- 2005
- Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose.
- Br J Ophthalmol 2005; Dec;89(12): 1638-42
081
R Kirwan, C Fenerty, J Crean, R Wordinger, A F Clark, C O’Brien
- 2005
- Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro.
- Mol Vis 2005 Sep 23;11:798-810
080
R Kirwan, M O’Leonard, M Murphy A F Clark, C O’Brien
- 2005
- Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells.
- Glia. 2005 Dec;52(4):309-24.
079
VW Long, C O’Brien.
- 2005
- Trends in ophthalmic surgery in Ireland.
- Irish Journal Med. Sci 2005; 174 (2); 36-39
078
P Aspinall, A Hill, P Nelson, C O’Brien, E O’Connell, L McCloughan, A Azuara-Blanco, R Brice, S Green, C Steeds.
- 2005
- Quality of life in patients with glaucoma: a conjoint analysis approach.
- Visual Impairment Research 2005; 7 (1): 13-26.
077
T E Walshe, G Ferguson, P Connell, C O’Brien, P A Cahill.
- 2005
- Pulsatile flow increases the expression of eNOS, ET-1, and Prostacyclin in a novel in vitro coculture model of the retinal vasculature.
- Invest Ophthal Vis Sci 2005;Jan(46)1:375-382.
076
C Cleary, C H Buckley, E Henry, P McLoughlin, C O’Brien, P W Hadoke.
- 2005
- Enhanced endothelium derived hyperpolarized factor activity in resistance arteries from normal pressure glaucoma patients: implications for vascular function in the eye.
- Br J Ophthalmol 2005;89:223-228
075
S L Ho, G F Dogar, J Wang, J Crean, Q D Wu, N Oliver, S Weitz, A Murray, P E Cleary, C O’Brien.
- 2005
- Elevated aqueous humour tissue inhibitor of matrix metalloproteinase-1 and connective tissue growth factor in pseudoexfoliation disease.
- Br J Ophthalmol 2005;89:169-173.
074
Morgan-Davies J, Taylor N, Hill AR, Aspinall P, O’Brien CJ, Asuara-Blanco A.
- 2004
- Three dimensional analysis of the lamina cribrosa in glaucoma.
- Br J Ophthalmol 2004 Oct;88(10): 1299-304.
073
R Kirwan, J Crean, C Fenerty, A Clark, C O’Brien.
- 2004
- Effect of cyclical mechanical stretch and exogenous transforming growth factor-B1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
- J Glaucoma 2004 Aug; 13(4): 327-34.
072
J Stokes, R Best, C O’Brien, J Seckl.
- 2003
- Altered glucocorticoid peripheral sensitivity in glaucoma.
- Invest Ophthal Vis Sci 2003; Dec 44(12) 5163-7.
071
J Kerr, C O’Brien.
- 2003
- Ocular blood flow in untreated ocular hypertension.
- Am J Ophthalmology 2003 Dec 136(6) 1106-13.
070
S Quinn, C O’Brien, P McLoughlin.
- 2003
- Nitric oxide independent vasorelaxation in the bovine long posterior ciliary artery.
- Eye 2003 July 17(5) 628-36.
069
P Nelson, P Aspinall, C O’Brien.
- 2003
- The relationship between quality of life and visual function in glaucoma.
- J Glaucoma 2003 Apr 12(2) 139-50.
068
Buckley C, Hadoke P, Henry E, O’Brien C.
- 2002
- Systemic vascular endothelial dysfunction in normal pressure glaucoma
- Br J Ophthalmology 2002; 86; 227-32.
067
O’Toole L, Cahill M, O’Brien C.
- 2001
- Eyelid hypertrichosis associated with latanoprost is reversible.
- Eur J Ophthalmol. 2001 Oct-Dec;11(4):377-9.
066
Devlin H, O’Brien C.
- 2001
- Normal tension glaucoma: Diagnosis and Management.
- CME Journal Ophthalmol 2001; 5(1): 13-17.
065
Morgan-Davies J, King A, Aspinall P, O’Brien C.
- 2000
- Measurement of a novel optic disc topographic parameter ‘spikiness’ in glaucoma.
- Graefe’s Arch Clin Exp Ophthalmol 2000, 238: 669- 76.
064
McKinnon J, McKillop G, Swa K, O’Brien C, Butt Z, Nelson P.
- 2000
- Colour Doppler imaging of the ocular circulation in diabetic retinopathy.
- Acta Ophthalmol, 2000, 78: 386-9.
063
Stokes J, Andrew R, Seckyl J, O’Brien C.
- 2000
- Glucocorticoid and mineralocorticoid receptors and 11-beta-deyhydrogenase activity in rat and human ocular tissue.
- Invest Ophthalmol Vis Sci 2000; 41: 1629-38.
062
King A, Bolton N, Aspinall P, O’Brien C.
- 2000
- Retinal nerve fibre layer volume in glaucoma.
- Am J Ophthalmol 2000, 129: 599-607.
061
J Stokes, E Henry, C O’Brien.
- 1998/1999
- Differential Diagnosis of Normal Tension Glaucoma (1998)
- In: Pillunat L, Harris A (eds) Fortbildurg Glaucoma. Enke Verlag, Stuggart, 1999.
060
O’Brien C, Butt Z.
- 1999
- Blood flow velocity in the peripheral circulation of glaucoma patients.
- Ophthalmologica 1999; 213: 150-153.
059
Henry E, Newby DE, Webb DJ, O’Brien C.
- 1999
- Peripheral endothelial dysfunction in normal pressure glaucoma.
- Invest Ophthalmol Vis Sci 1999; 40: 1710-1714.
058
Nelson P, Aspinall P, O’Brien C.
- 1999
- Patients’ perception of visual impairment in glaucoma. A pilot study.
- Br J Ophthalmol 1999; 83: 546-552.
057
Edgar DF, Crabb DP, Rudnicka AR, Lawrensen JG, Gutteridge NM, O’Brien C.
- 1999
- Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and Logmar acuity.
- Graefe’s Arch Clin Exp Ophthalmol 1999; 237: 117-24.
056
Buckley C H, Hadoke P, O’Brien C.
- 1998
- Role of the endothelium in modulating functional responses of isolated bovine anterior ciliary arteries to vasoconstrictor agonists.
- Br J Ophthalmol 1998; 82: 826-829.
055
Fontana L, Poinoosawmy D, Bunce CV, O’Brien C, Hitchings RA.
- 1998
- Pulsatile ocular blood flow investigation in asymmetric normal-tension glaucoma and normal subjects.
- Br J Ophthalmol 1998; 82: 731-6.
054
Kelly PA, Buckley C, Ritchie IM, O’Brien C.
- 1998
- Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat.
- Br J Ophthalmol 1998; 82: 1199-202.
053
O’Brien C
- 1998
- Vasospasm and glaucoma (Editorial).
- Br J Ophthalmol 1998; 82: 855-6.
052
Kerr J, Nelson P, O’Brien C.
- 1998
- A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension.
- Am J Ophthalmol 1998; 126: 42-51.
051
C. O’Brien.
- 1998
- Is there a role for computerised image analysis in glaucoma management.
- Br. J Ophthalmol 1998, 82: 2-3. (Editorial).
050
C Buckley, P Hadoke, C O’Brien.
- 1997
- The use of isolated ocular arteries in-vitro to define the pathology of vascular changes in glaucoma.
- Br J Ophthalmol 1997, 81:599 - 607
049
JR Mackinnon, Z Butt, K Swa, C O’Brien.
- 1997
- Pulsatile ocular blood flow in untreated diabetic retinopathy.
- Acta Ophthalmol, 1997; 75:6, 661-4.
048
RWD Bell, NE Habib, C O’Brien.
- 1997
- Long-term outcome and complications of trabeculectomy with a single per-operative application of 5-fluorouracil.
- Eye 1997;11: 663-71.
047
RS Anderson, C O’Brien.
- 1997
- Psychophysical evidence for selective loss of M ganglion cells in glaucoma
- Vis Res 1997 , 37: 1079-1083.
046
RWD Bell, HK Yang, C O’Brien.
- 1997
- A case of bilateral cavernous hemangioma associated with intra-cerebral hemangioma.
- Arch Ophthalmol 1997, 115:6, 818-9.
045
C O’Brien, Z Butt, C Ludlum.
- 1997
- Activation of the coagulation cascade in untreated primary open angle glaucoma.
- Ophthalmol 1997; 104:725 - 730
044
Z Butt, C O’Brien, G McKillop, P Aspinall, P Allan.
- 1997
- Colour Doppler imaging in untreated high and normal pressure open angle glaucoma.
- Invest Ophthalmol Vis Sci, 1997; 38: 690-6.
043
C O’Brien, P Kelly, I Ritchie.
- 1997
- The effect of chronic inhibition of nitric oxide synthase on ocular blood flow and glucose metabolism in rats.
- Br J Ophthalmol 1997;81:68-71.
042
RWD Bell, C O’Brien.
- 1997
- Accuracy of referral to a glaucoma clinic.
- Ophthal Physiol Opt 1997;17:7-11.
041
RWD Bell, C O’Brien.
- 1997
- Diagnostic outcome of hospital glaucoma referrals.
- Ophthal Physiol Opt 1997;17:3-6.
040
A Kosmin, M Austin, C.O’Brien, N. Cotu, P. Wishart.
- 1996/1997
- Ageing changes in automated perimetry. A comparison of flicker and luminance sensitivity in normal subjects.
- In: Wall M, Heijl A (eds). Perimetry update 1996/1997. Kugler: Amsterdam, New York 1997, pp 229 - 233.
039
FD Ghanchi, TH Williamson, CS Lim, Z Butt, GM Baxter, G McKillop, C O’Brien.
- 1996
- Colour Doppler imaging in giant cell (temporal) arteritis: serial examination and comparison with non-arteritic anterior ischaemic optic neuropathy.
- Eye 1996;10:459-464.
038
C Lim, C O’Brien, N Bolton.
- 1996
- A simple clinical method to measure the optic disc size in glaucoma.
- J Glaucoma 1996;5:241-245.
037
J Sing, R Bell, A Adams, C O’Brien,
- 1996
- Enhancement of post trabeculectomy bleb formation by laser suture lysis.
- Br J Ophthalmol 1996;80:624-627.
036
RS Ayyala, C O’Brien, I Grierson, P Maltby.
- 1996
- Transcleral flow of aqueous humor: an in-vitro experiment.
- Ophthalmol Surg 1996;27:66-69.
035
M Birch, S Barbosa, L Blumhardt, C O Brien, S Harding.
- 1996
- Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis.
- Arch Ophthalmol 1996;114-119.
034
RS Anderson, P Detkova, C O’Brien.
- 1995
- Effect of temporal frequency and contrast on peripheral grating resolution.
- Curr Eye Res 1995;14:1031-1033.
033
GP Rao, C O’Brien, MH Dwyer, A Patterson.
- 1995
- Rapid onset bilateral calcific band keratopathy associated with phosphate containing steroid eye drops.
- Eur J Implant Refr Surg 1995;7:251-252.
032
A King, D David, H Jones, C O’Brien.
- 1995
- Non-attendance at an ophthalmic out-patient department.
- J Roy Soc Med 1995;88:88-90.
031
J Sing, H Chawla, C O’Brien.
- 1995
- Success rate and complications of intraoperative mitomycin-C in trabeculectomy surgery.
- Eye 1995;9:460-466.
030
Z Butt, C O’Brien.
- 1995
- Reproducibility of pulsatile ocular blood flow measurements.
- J Glaucoma 1995;4:214-218.
029
C O’Brien, J Wild.
- 1995
- Automated perimetry in glaucoma - room for improvement?
- Br J Ophthalmol 1995;79:200-201. (editorial)
028
Z Butt, G McKillop, C O’Brien, P Allan, P Aspinall.
- 1995
- Measurement of ocular blood flow velocity using colour Doppler imaging in low tension glaucoma.
- Eye 1995, 9:29-33.
027
D. Broadway, I Grierson, C O’Brien, R Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part II. The outcome of filtration surgery.
- Arch Ophthalmol 1994;112:1446-1454.
026
D Broadway, I Grierson, C O’Brien, RA Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part I. The conjunctival cell profile.
- Arch Ophthalmol 1994;112:1437-1445.
025
C de Vivero, C O’Brien, L Lanigan, RA Hitchings.
- 1994
- Diurnal intraocular pressure variation in low tension glaucoma.
- Eye 1994;8:521-523.
024
C O’Brien, D Clark.
- 1994
- Ocular biometry in preterm infants without retinopathy of prematurity.
- Eye 1994;8:662-665.
023
M Austin, C O’Brien, P Wishart.
- 1994
- Flicker perimetry using a luminance threshold strategy at frequencies from 5-25Hz in glaucoma, ocular hypertension and normal controls.
- Curr Eye Res 1994;13:7171-724.
022
DE Laws, R Haslett, D Ashby, C O’Brien, D Clark.
- 1994
- Axial length biometry in infants with retinopathy of prematurity.
- Eye 1994;8:427-430.
021
C O’Brien, D Poinoosawmy, J Wu, R Hitchings.
- 1994
- Evaluation of a rapid thresholding program (Fastpac) in glaucoma.
- Br J Ophthalmol 1994;78:516-9.
020
MW Austin, C O’Brien, PE Wishart.
- 1994/1995
- Forced choice flicker perimetry in glaucoma.
- In: Perimetry Update 1994/1995; (eds) RP Mills, M Wall. Kugler Publ, Amsterdam, pp 135-140.
019
K. Evans, C O’Brien, A Patterson.
- 1994
- Corneal endothelial response to corticosteroid in cataract surgery.
- Eur J Implant Refr Surg 1994;6:74-78.
018
B Moriarty, C O’Brien.
- 1993
- Cataract surgery in the glaucoma patient.
- In: Ball S, Franklin R (eds); Trans New Orleans and Acad Ophthalmol - Glaucoma, Diagnosis and Therapy 1993. Kugler Publ, Amstelveen pp 159-168.
017
J. Singh, C O’Brien, M Wright.
- 1993
- Nebulised bronchodilator therapy causes acute angle closure glaucoma in predisposed individuals.
- Resp Med 1993, 187:559-561
016
C O’Brien, JD Young, M Brown, C Short, M Bone.
- 1993
- Electrophysiology of type 2 mesangio-capillary glomerulonephritis with associated fundus abnormalities.
- Br J Ophthalmol 1993;77:778-780.
015
L Lanigan, C O’Brien, R Hitchings.
- 1992
- “Bubble sight”.
- BMJ (Minerva) 1992;305:1588.
014
M Cox, C. O’Brien.
- 1992
- Comparison of computer assisted versus manual optic nerve head pallor measurement.
- Invest Ophthalmol Vis Sci 1992;33:3169-3173.
013
D. Clark, C O’Brien, M Weindling, M Saed.
- 1992
- Initial experience of screening for retinopathy of prematurity.
- Arch Dis Child 1992;67:1233-1236.
012
C. O’Brien, V Saxton, RP Crick, HB Meire.
- 1992
- Doppler carotid artery studies in asymmetric glaucoma.
- Eye 1992;6:273-276
011
D. Poinoosawmy, J Sturmer, C O’Brien, J Wu, R Hitchings.
- 1992
- Is diffuse visual field loss in low tension glaucoma a prognostic indicator for progression.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ. Amsterdam, pp 121-127.
010
C O’Brien, M Austin, P Wareing, P Hammond.
- 1992
- Clinical evaluation of a new combined automated flicker and static perimeter.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ: Amsterdam, pp 603-606.
009
C O’Brien, B Schwartz.
- 1992
- Point by point linear regression analysis of automated visual fields in chronic open angle glaucoma.
- In: Perimetry Update 1992/93; Mills RP (ed). Kugler Publ, Amsterdam, pp 149-152.
008
C. O’Brien, B Schwartz, T Takamoto.
- 1991
- Correlation of optic disc cupping, pallor and retinal nerve fibre layer thickness with visual field loss in chronic open angle glaucoma.
- In: Perimetry Update 1991; eds Mills and Heijl: Kugler Publ, Amsterdam pp15-19.
007
C. O’Brien. Optic disc pallor measurement.
- 1991
- Optic disc pallor measurement.
- Eye 1991;5:763.
006
J. Butcher, C. O’Brien.
- 1991
- The reproducibility of biometry and keratometry.
- Eye 1991;5:708-711.
005
C. O’Brien, B Schwartz, T Takamoto, DC Wu.
- 1991
- Intraocular pressure and the rate of change of the visual field in chronic open angle glaucoma.
- Am J Ophthalmol 1991;111:491-497.
004
McAllister, C. O’Brien. Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- 1990
- Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- Eye 1990;4:651-654.
003
C. O’Brien, B Schwartz. The visual field in chronic open angle glaucoma:
- 1990
- The visual field in chronic open angle glaucoma: the rate of change in the different regions of the field.
- Eye 1990;4:557-562.
002
CJ O’Brien, I Grierson, J McAllister. Treatment parameters for
- 1990
- transcleral cyclocoagulation with the Neodymium:Yag laser.
- Lasers Ophthalmol 1990;3:221-225.
001
C J O’Brien, GM Kyle
- 1988
- Metastatic staphylococcus aureas endophthalmitis:
- Br J Ophthalmol 1988;72:189-91.
Showing 1 - 180 out of 180
001
C J O’Brien, GM Kyle
- 1988
- Metastatic staphylococcus aureas endophthalmitis:
- Br J Ophthalmol 1988;72:189-91.
002
CJ O’Brien, I Grierson, J McAllister. Treatment parameters for
- 1990
- transcleral cyclocoagulation with the Neodymium:Yag laser.
- Lasers Ophthalmol 1990;3:221-225.
003
C. O’Brien, B Schwartz. The visual field in chronic open angle glaucoma:
- 1990
- The visual field in chronic open angle glaucoma: the rate of change in the different regions of the field.
- Eye 1990;4:557-562.
004
McAllister, C. O’Brien. Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- 1990
- Neodymium:Yag transcleral cyclocoagulation: a clinical study.
- Eye 1990;4:651-654.
005
C. O’Brien, B Schwartz, T Takamoto, DC Wu.
- 1991
- Intraocular pressure and the rate of change of the visual field in chronic open angle glaucoma.
- Am J Ophthalmol 1991;111:491-497.
006
J. Butcher, C. O’Brien.
- 1991
- The reproducibility of biometry and keratometry.
- Eye 1991;5:708-711.
007
C. O’Brien. Optic disc pallor measurement.
- 1991
- Optic disc pallor measurement.
- Eye 1991;5:763.
008
C. O’Brien, B Schwartz, T Takamoto.
- 1991
- Correlation of optic disc cupping, pallor and retinal nerve fibre layer thickness with visual field loss in chronic open angle glaucoma.
- In: Perimetry Update 1991; eds Mills and Heijl: Kugler Publ, Amsterdam pp15-19.
009
C O’Brien, B Schwartz.
- 1992
- Point by point linear regression analysis of automated visual fields in chronic open angle glaucoma.
- In: Perimetry Update 1992/93; Mills RP (ed). Kugler Publ, Amsterdam, pp 149-152.
010
C O’Brien, M Austin, P Wareing, P Hammond.
- 1992
- Clinical evaluation of a new combined automated flicker and static perimeter.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ: Amsterdam, pp 603-606.
011
D. Poinoosawmy, J Sturmer, C O’Brien, J Wu, R Hitchings.
- 1992
- Is diffuse visual field loss in low tension glaucoma a prognostic indicator for progression.
- In: Mills RP (ed). Perimetry Update 1992/93. Kugler Publ. Amsterdam, pp 121-127.
012
C. O’Brien, V Saxton, RP Crick, HB Meire.
- 1992
- Doppler carotid artery studies in asymmetric glaucoma.
- Eye 1992;6:273-276
013
D. Clark, C O’Brien, M Weindling, M Saed.
- 1992
- Initial experience of screening for retinopathy of prematurity.
- Arch Dis Child 1992;67:1233-1236.
014
M Cox, C. O’Brien.
- 1992
- Comparison of computer assisted versus manual optic nerve head pallor measurement.
- Invest Ophthalmol Vis Sci 1992;33:3169-3173.
015
L Lanigan, C O’Brien, R Hitchings.
- 1992
- “Bubble sight”.
- BMJ (Minerva) 1992;305:1588.
016
C O’Brien, JD Young, M Brown, C Short, M Bone.
- 1993
- Electrophysiology of type 2 mesangio-capillary glomerulonephritis with associated fundus abnormalities.
- Br J Ophthalmol 1993;77:778-780.
017
J. Singh, C O’Brien, M Wright.
- 1993
- Nebulised bronchodilator therapy causes acute angle closure glaucoma in predisposed individuals.
- Resp Med 1993, 187:559-561
018
B Moriarty, C O’Brien.
- 1993
- Cataract surgery in the glaucoma patient.
- In: Ball S, Franklin R (eds); Trans New Orleans and Acad Ophthalmol - Glaucoma, Diagnosis and Therapy 1993. Kugler Publ, Amstelveen pp 159-168.
019
K. Evans, C O’Brien, A Patterson.
- 1994
- Corneal endothelial response to corticosteroid in cataract surgery.
- Eur J Implant Refr Surg 1994;6:74-78.
020
MW Austin, C O’Brien, PE Wishart.
- 1994/1995
- Forced choice flicker perimetry in glaucoma.
- In: Perimetry Update 1994/1995; (eds) RP Mills, M Wall. Kugler Publ, Amsterdam, pp 135-140.
021
C O’Brien, D Poinoosawmy, J Wu, R Hitchings.
- 1994
- Evaluation of a rapid thresholding program (Fastpac) in glaucoma.
- Br J Ophthalmol 1994;78:516-9.
022
DE Laws, R Haslett, D Ashby, C O’Brien, D Clark.
- 1994
- Axial length biometry in infants with retinopathy of prematurity.
- Eye 1994;8:427-430.
023
M Austin, C O’Brien, P Wishart.
- 1994
- Flicker perimetry using a luminance threshold strategy at frequencies from 5-25Hz in glaucoma, ocular hypertension and normal controls.
- Curr Eye Res 1994;13:7171-724.
024
C O’Brien, D Clark.
- 1994
- Ocular biometry in preterm infants without retinopathy of prematurity.
- Eye 1994;8:662-665.
025
C de Vivero, C O’Brien, L Lanigan, RA Hitchings.
- 1994
- Diurnal intraocular pressure variation in low tension glaucoma.
- Eye 1994;8:521-523.
026
D Broadway, I Grierson, C O’Brien, RA Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part I. The conjunctival cell profile.
- Arch Ophthalmol 1994;112:1437-1445.
027
D. Broadway, I Grierson, C O’Brien, R Hitchings.
- 1994
- Adverse effects of topical anti-glaucoma medications. Part II. The outcome of filtration surgery.
- Arch Ophthalmol 1994;112:1446-1454.
028
Z Butt, G McKillop, C O’Brien, P Allan, P Aspinall.
- 1995
- Measurement of ocular blood flow velocity using colour Doppler imaging in low tension glaucoma.
- Eye 1995, 9:29-33.
029
C O’Brien, J Wild.
- 1995
- Automated perimetry in glaucoma - room for improvement?
- Br J Ophthalmol 1995;79:200-201. (editorial)
030
Z Butt, C O’Brien.
- 1995
- Reproducibility of pulsatile ocular blood flow measurements.
- J Glaucoma 1995;4:214-218.
031
J Sing, H Chawla, C O’Brien.
- 1995
- Success rate and complications of intraoperative mitomycin-C in trabeculectomy surgery.
- Eye 1995;9:460-466.
032
A King, D David, H Jones, C O’Brien.
- 1995
- Non-attendance at an ophthalmic out-patient department.
- J Roy Soc Med 1995;88:88-90.
033
GP Rao, C O’Brien, MH Dwyer, A Patterson.
- 1995
- Rapid onset bilateral calcific band keratopathy associated with phosphate containing steroid eye drops.
- Eur J Implant Refr Surg 1995;7:251-252.
034
RS Anderson, P Detkova, C O’Brien.
- 1995
- Effect of temporal frequency and contrast on peripheral grating resolution.
- Curr Eye Res 1995;14:1031-1033.
035
M Birch, S Barbosa, L Blumhardt, C O Brien, S Harding.
- 1996
- Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis.
- Arch Ophthalmol 1996;114-119.
036
RS Ayyala, C O’Brien, I Grierson, P Maltby.
- 1996
- Transcleral flow of aqueous humor: an in-vitro experiment.
- Ophthalmol Surg 1996;27:66-69.
037
J Sing, R Bell, A Adams, C O’Brien,
- 1996
- Enhancement of post trabeculectomy bleb formation by laser suture lysis.
- Br J Ophthalmol 1996;80:624-627.
038
C Lim, C O’Brien, N Bolton.
- 1996
- A simple clinical method to measure the optic disc size in glaucoma.
- J Glaucoma 1996;5:241-245.
039
FD Ghanchi, TH Williamson, CS Lim, Z Butt, GM Baxter, G McKillop, C O’Brien.
- 1996
- Colour Doppler imaging in giant cell (temporal) arteritis: serial examination and comparison with non-arteritic anterior ischaemic optic neuropathy.
- Eye 1996;10:459-464.
040
A Kosmin, M Austin, C.O’Brien, N. Cotu, P. Wishart.
- 1996/1997
- Ageing changes in automated perimetry. A comparison of flicker and luminance sensitivity in normal subjects.
- In: Wall M, Heijl A (eds). Perimetry update 1996/1997. Kugler: Amsterdam, New York 1997, pp 229 - 233.
041
RWD Bell, C O’Brien.
- 1997
- Diagnostic outcome of hospital glaucoma referrals.
- Ophthal Physiol Opt 1997;17:3-6.
042
RWD Bell, C O’Brien.
- 1997
- Accuracy of referral to a glaucoma clinic.
- Ophthal Physiol Opt 1997;17:7-11.
043
C O’Brien, P Kelly, I Ritchie.
- 1997
- The effect of chronic inhibition of nitric oxide synthase on ocular blood flow and glucose metabolism in rats.
- Br J Ophthalmol 1997;81:68-71.
044
Z Butt, C O’Brien, G McKillop, P Aspinall, P Allan.
- 1997
- Colour Doppler imaging in untreated high and normal pressure open angle glaucoma.
- Invest Ophthalmol Vis Sci, 1997; 38: 690-6.
045
C O’Brien, Z Butt, C Ludlum.
- 1997
- Activation of the coagulation cascade in untreated primary open angle glaucoma.
- Ophthalmol 1997; 104:725 - 730
046
RWD Bell, HK Yang, C O’Brien.
- 1997
- A case of bilateral cavernous hemangioma associated with intra-cerebral hemangioma.
- Arch Ophthalmol 1997, 115:6, 818-9.
047
RS Anderson, C O’Brien.
- 1997
- Psychophysical evidence for selective loss of M ganglion cells in glaucoma
- Vis Res 1997 , 37: 1079-1083.
048
RWD Bell, NE Habib, C O’Brien.
- 1997
- Long-term outcome and complications of trabeculectomy with a single per-operative application of 5-fluorouracil.
- Eye 1997;11: 663-71.
049
JR Mackinnon, Z Butt, K Swa, C O’Brien.
- 1997
- Pulsatile ocular blood flow in untreated diabetic retinopathy.
- Acta Ophthalmol, 1997; 75:6, 661-4.
050
C Buckley, P Hadoke, C O’Brien.
- 1997
- The use of isolated ocular arteries in-vitro to define the pathology of vascular changes in glaucoma.
- Br J Ophthalmol 1997, 81:599 - 607
051
C. O’Brien.
- 1998
- Is there a role for computerised image analysis in glaucoma management.
- Br. J Ophthalmol 1998, 82: 2-3. (Editorial).
052
Kerr J, Nelson P, O’Brien C.
- 1998
- A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension.
- Am J Ophthalmol 1998; 126: 42-51.
053
O’Brien C
- 1998
- Vasospasm and glaucoma (Editorial).
- Br J Ophthalmol 1998; 82: 855-6.
054
Kelly PA, Buckley C, Ritchie IM, O’Brien C.
- 1998
- Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat.
- Br J Ophthalmol 1998; 82: 1199-202.
055
Fontana L, Poinoosawmy D, Bunce CV, O’Brien C, Hitchings RA.
- 1998
- Pulsatile ocular blood flow investigation in asymmetric normal-tension glaucoma and normal subjects.
- Br J Ophthalmol 1998; 82: 731-6.
056
Buckley C H, Hadoke P, O’Brien C.
- 1998
- Role of the endothelium in modulating functional responses of isolated bovine anterior ciliary arteries to vasoconstrictor agonists.
- Br J Ophthalmol 1998; 82: 826-829.
057
Edgar DF, Crabb DP, Rudnicka AR, Lawrensen JG, Gutteridge NM, O’Brien C.
- 1999
- Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and Logmar acuity.
- Graefe’s Arch Clin Exp Ophthalmol 1999; 237: 117-24.
058
Nelson P, Aspinall P, O’Brien C.
- 1999
- Patients’ perception of visual impairment in glaucoma. A pilot study.
- Br J Ophthalmol 1999; 83: 546-552.
059
Henry E, Newby DE, Webb DJ, O’Brien C.
- 1999
- Peripheral endothelial dysfunction in normal pressure glaucoma.
- Invest Ophthalmol Vis Sci 1999; 40: 1710-1714.
060
O’Brien C, Butt Z.
- 1999
- Blood flow velocity in the peripheral circulation of glaucoma patients.
- Ophthalmologica 1999; 213: 150-153.
061
J Stokes, E Henry, C O’Brien.
- 1998/1999
- Differential Diagnosis of Normal Tension Glaucoma (1998)
- In: Pillunat L, Harris A (eds) Fortbildurg Glaucoma. Enke Verlag, Stuggart, 1999.
062
King A, Bolton N, Aspinall P, O’Brien C.
- 2000
- Retinal nerve fibre layer volume in glaucoma.
- Am J Ophthalmol 2000, 129: 599-607.
063
Stokes J, Andrew R, Seckyl J, O’Brien C.
- 2000
- Glucocorticoid and mineralocorticoid receptors and 11-beta-deyhydrogenase activity in rat and human ocular tissue.
- Invest Ophthalmol Vis Sci 2000; 41: 1629-38.
064
McKinnon J, McKillop G, Swa K, O’Brien C, Butt Z, Nelson P.
- 2000
- Colour Doppler imaging of the ocular circulation in diabetic retinopathy.
- Acta Ophthalmol, 2000, 78: 386-9.
065
Morgan-Davies J, King A, Aspinall P, O’Brien C.
- 2000
- Measurement of a novel optic disc topographic parameter ‘spikiness’ in glaucoma.
- Graefe’s Arch Clin Exp Ophthalmol 2000, 238: 669- 76.
066
Devlin H, O’Brien C.
- 2001
- Normal tension glaucoma: Diagnosis and Management.
- CME Journal Ophthalmol 2001; 5(1): 13-17.
067
O’Toole L, Cahill M, O’Brien C.
- 2001
- Eyelid hypertrichosis associated with latanoprost is reversible.
- Eur J Ophthalmol. 2001 Oct-Dec;11(4):377-9.
068
Buckley C, Hadoke P, Henry E, O’Brien C.
- 2002
- Systemic vascular endothelial dysfunction in normal pressure glaucoma
- Br J Ophthalmology 2002; 86; 227-32.
069
P Nelson, P Aspinall, C O’Brien.
- 2003
- The relationship between quality of life and visual function in glaucoma.
- J Glaucoma 2003 Apr 12(2) 139-50.
070
S Quinn, C O’Brien, P McLoughlin.
- 2003
- Nitric oxide independent vasorelaxation in the bovine long posterior ciliary artery.
- Eye 2003 July 17(5) 628-36.
071
J Kerr, C O’Brien.
- 2003
- Ocular blood flow in untreated ocular hypertension.
- Am J Ophthalmology 2003 Dec 136(6) 1106-13.
072
J Stokes, R Best, C O’Brien, J Seckl.
- 2003
- Altered glucocorticoid peripheral sensitivity in glaucoma.
- Invest Ophthal Vis Sci 2003; Dec 44(12) 5163-7.
073
R Kirwan, J Crean, C Fenerty, A Clark, C O’Brien.
- 2004
- Effect of cyclical mechanical stretch and exogenous transforming growth factor-B1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
- J Glaucoma 2004 Aug; 13(4): 327-34.
074
Morgan-Davies J, Taylor N, Hill AR, Aspinall P, O’Brien CJ, Asuara-Blanco A.
- 2004
- Three dimensional analysis of the lamina cribrosa in glaucoma.
- Br J Ophthalmol 2004 Oct;88(10): 1299-304.
075
S L Ho, G F Dogar, J Wang, J Crean, Q D Wu, N Oliver, S Weitz, A Murray, P E Cleary, C O’Brien.
- 2005
- Elevated aqueous humour tissue inhibitor of matrix metalloproteinase-1 and connective tissue growth factor in pseudoexfoliation disease.
- Br J Ophthalmol 2005;89:169-173.
076
C Cleary, C H Buckley, E Henry, P McLoughlin, C O’Brien, P W Hadoke.
- 2005
- Enhanced endothelium derived hyperpolarized factor activity in resistance arteries from normal pressure glaucoma patients: implications for vascular function in the eye.
- Br J Ophthalmol 2005;89:223-228
077
T E Walshe, G Ferguson, P Connell, C O’Brien, P A Cahill.
- 2005
- Pulsatile flow increases the expression of eNOS, ET-1, and Prostacyclin in a novel in vitro coculture model of the retinal vasculature.
- Invest Ophthal Vis Sci 2005;Jan(46)1:375-382.
078
P Aspinall, A Hill, P Nelson, C O’Brien, E O’Connell, L McCloughan, A Azuara-Blanco, R Brice, S Green, C Steeds.
- 2005
- Quality of life in patients with glaucoma: a conjoint analysis approach.
- Visual Impairment Research 2005; 7 (1): 13-26.
079
VW Long, C O’Brien.
- 2005
- Trends in ophthalmic surgery in Ireland.
- Irish Journal Med. Sci 2005; 174 (2); 36-39
080
R Kirwan, M O’Leonard, M Murphy A F Clark, C O’Brien
- 2005
- Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells.
- Glia. 2005 Dec;52(4):309-24.
081
R Kirwan, C Fenerty, J Crean, R Wordinger, A F Clark, C O’Brien
- 2005
- Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro.
- Mol Vis 2005 Sep 23;11:798-810
082
R Kane, L Stevenson, C Godson, A Stitt, C O’Brien.
- 2005
- Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose.
- Br J Ophthalmol 2005; Dec;89(12): 1638-42
083
A Knox, M Barry, C O’Brien.
- 2006
- The rising cost of glaucoma drugs in Ireland. 1996-2003.
- Br J Ophthalmol 2006 Feb;90(2):162-5
084
McKernan DP, Caplis C, Donovan M, O’Brien C, Cotter T.
- 2006
- Age-dependent susceptibility of the retinal ganglion cell layer to cell death.
- Invest Ophthalmol Vis Sci. 2006 Mar;47(3):807-14.
085
C Kelliher, D Kenny, C O’Brien.
- 2006
- Trends in blind registration in the adult population of the Republic of Ireland. 1996-2003.
- Br J Ophthalmol 2006 Mar;90(3)367-71.
086
L Cryan, G Pidgeon, D Fitzgerald, C O’Brien.
- 2006
- COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
- Mol Vis. 2006 Apr 20;12:405-14
087
E Henry, D Newby, DJ Webb, PW Hadoke, C O’Brien.
- 2006
- Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma.
- Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2528-32.
088
Y Delaney, T Walshe, C O’Brien.
- 2006
- Vasospasm in glaucoma: clinical and laboratory aspects.
- Optom Vis Sci. 2006 Jul;83(7):406-14.
089
Guerin MB, McKernan DP, O’Brien CJ, Cotter TG.
- 2006
- Retinal ganglion cells: dying to survive.
- Int J Dev Biol. 2006;50(8):665-74..
090
McKernan DP, Guerin MB, O’Brien CJ, Cotter TG. A key role for calpains in retinal ganglion cell death.
- 2007
- Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5420-30.
091
Lee H, O’Meara SJ, O’Brien C, Kane R.
- 2007
- The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy.
- Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4291-9.
092
Connell P, Walshe T, Ferguson G, Gao W, O’Brien C, Cahill PA.
- 2007
- Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells.
- Endothelium. 2007 Jan-Feb;14(1):17-24.
093
Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O’Brien C, Cahill PA.
- 2007
- High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.
- J Mol Cell Cardiol. 2007 Mar;42(3):609-19. Epub 2006 Dec 21.
094
Horgan N, Kirwan RP, O’Brien CJ.
- 2007
- Choroidal detachment associated with latanoprost use in the fellow eye.
- Ann Pharmacother. 2007 Jan;41(1):161-2.
095
Cryan LM, Paraoan L, Hiscott P, Damato BE, Grierson I, Gray D, Farrell M, Doherty GA, Fitzgerald DJ, O’Brien C.
- 2008
- Expression of COX-2 and prognostic outcome in uveal melanoma.
- Curr Eye Res. 2008 Feb;33(2):177-84.
096
Aragon-Martin JA, Ritch R, Liebmann J, O’Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Damji KF, Tarkkanen A, Rezaie T, Child AH, Sarfarazi M.
- 2008
- Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
- Mol Vis. 2008 Mar 17;14:533-41.
097
O’Driscoll C, O’Connor J, O’Brien CJ, Cotter TG.
- 2008
- Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
- J Neurochem. 2008 Apr;105(2):524-36. Epub 2007 Dec 13.
098
Kane R, Godson C, O’Brien C.
- 2008
- Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
- Mol Vis. 2008 Jun 20;14:1138-48.
099
O’Connor JC, Wallace DM, O’Brien C, Cotter TG. A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- 2008
- A novel antioxidant function for the tumour suppressor gene p53 in the retinal ganglion cell.
- Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4237-44
100
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O’Brien C, Walls D, Redmond EM, Cahill PA.
- 2008
- Notch and vascular smooth muscle cell phenotype.
- Circ Res. 2008 Dec 5;103(12):1370-82.
101
Cryan L, O’Brien C.
- 2008
- Proteomics as a research tool in clinical and experimental ophthalmology.
- Proteomics Clin. App. 2008; 2(5); 762-75
102
Guerin M, Flynn T, Brady J, O’Brien C.
- 2008
- Worldwide geographical distribution of ophthalmic publications.
- Int Ophthalmol; 2008; 29: 511-6.
103
Cryan L, Fitzgerald D, O’Brien C.
- 2009
- Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclogenase.
- Prostaglandins, Leuko & Essent Fatty Acids 2009 81:401-9.
104
Irnaten M, Barry RC, Quill B, Clark AF, Harvey BJ, O’Brien CJ.
- 2009
- Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells.
- Invest Ophthalmol Vis Sci. 2009 Jan;50(1):194-202. Epub 2008 Sep 4.
105
Kirwan RP, Wordinger RJ, Clark AF, O’Brien CJ.
- 2009
- Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells.
- Mol Vis. 2009;15:76-88. Epub 2009 Jan 15.
106
Quaranta L, Konstas AG, Rossetti L, Garcia-Feijoo J, O’Brien C, Nasr MB, Fogagnolo P, Demos CM, Stewart JA, Stewart WC.
- 2010
- Untreated 24-h intraocular pressures measured with Goldmann applanation tonometry vs nighttime supine pressures with Perkins applanation tonometry.
- Eye (Lond). 2010 Jul;24(7):1252-8. Epub 2009 Dec 4.
107
Dervan EW, Chen H, Ho SL, Brummel N, Schmid J, Toomey D, Haralambova M, Gould E, Wallace DM, Prehn JH, O’Brien C, Murphy D.
- 2010
- Protein Macroarray Profiling of Serum Autoantibodies in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2010 Jun;51(6):2968-75.
108
P O’Connor R, Cryan LM, Wynne K, de Stefani A, Fitzgerald D, O’Brien C, Cagney G.
- 2010
- Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.
- J Biomed Biotechnol. 2010; 2010:107859.
109
Walshe TE, Connell P, Cryan L, Ferguson G, O’Brien C, Cahill PA.
- 2011
- The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation.
- Cardiovasc Res. 2011 Feb 15;89(3):661-70.
110
Farrell SM, Groeger G, Bhatt L, Finnegan S, O’Brien CJ, Cotter TG.
- 2011
- bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.
- Eur J Neurosci. 2011 Feb;33(4):632-41.
111
Quill B, Docherty N, Clark AF, O’Brien CJ.
- 2011
- The Effect of Graded Cyclic Stretch on Extracellular Matrix Related Gene Expression Profiles in Cultured Primary Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2011; Mar 30;52(3):1908-15.
112
Guerin M, Cotter T, McKernan D, O’Brien C.
- 2011
- Age Dependent Rat Retinal Ganglion Cell Susceptibility to Apoptotic Stimuli: Implications for Glaucoma.
- Clin & Exper Ophthalmol Apr;39(3):243-51. 2011
113
McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF, O’Brien CJ, Wallace DM
- 2011
- Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.
- Mol Vis. 2011;17:1182-91.
114
Gallagher BA, Hart PM, O’Brien C, Stevenson MR, Jackson AJ.
- 2011
- Mobility and access to transport issues as experienced by people with vision impairment living in urban and rural Ireland.
- Disabil Rehabil. 2011;33(12):979-88.
115
Browne JG, Ho SL, Kane R, Oliver N, Clark AF, O’Brien CJ, Crean JK.
- 2011
- Connective Tissue Growth Factor is increased in Pseudoexfoliation Glaucoma.
- Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3660-6
116
Walshe TE, Connell P, Cryan L, Ferguson G, Gardiner T, Morrow D, Redmond EM, O’Brien C, Cahill PA
- 2011
- Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch signaling.
- Invest Ophthalmol Vis Sci. 2011 . Jun 23;52(7):4472-83.
117
Wiggs JL, Hewitt AW, Fan BJ, Wang DY, Figueiredo Sena DR, O’Brien C, Realini A, Craig JE, Dimasi DP, Mackey DA, Haines JL, Pasquale LR.
- 2012
- The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.
- PLoS One. 2012;7(9):e45613. doi: 10.1371/journal.pone.0045613. Epub 2012 Sep 26
118
Kirwan RP, Felice L, Clark AF, O’Brien CJ, Leonard MO.
- 2012
- Hypoxia regulated gene transcription in human optic nerve lamina cribrosa cells in culture.
- Invest Ophthalmol Vis Sci. 2012 53:2243-2255
119
Bhattacharya SK, Lee RK, Grus FH;
- 2013
- Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group. Molecular biomarkers in glaucoma.
- 2013 Jan 7;54(1):121-31
120
Igras E, Loughman J, Ratzlaff M, O’Caoimh R, O’Brien C.
- 2013
- Evidence of lower macular pigment optical density in chronic open angle glaucoma. Br J Ophthalmol. 2013 Aug;97(8):994-998
- Br J Ophthalmol. 2013 Aug;97(8):994-998
121
Irnaten M, Barry RC, Wallace DM, Docherty NG, Quill B, Clark AF, O’Brien CJ.
- 2013
- Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells
- Exp Eye Res 2013 Oct; 115:224-9
122
Wallace DM, Clarke AF, Lipson KE, Andrews D, Crean JK, O’Brien CJ .
- 2013
- Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells.
- Invest Ophthalmol Vis Sci 2013 Dec 2;54(13)7836-48
123
Wallace DM, Murphy-Ullrich JE, Downs JC, O’Brien CJ
- 2014
- The role of matricellular proteins in glaucoma.
- Matrix Biol 2014 Apr 12 pii S0945-053X(14)00058-4
124
McDonnell F, O’Brien C, Wallace D.
- 2014
- The role of epigenetics in the fibrotic processes associated with glaucoma.
- J Ophthalmol. 2014~:750459.
125
Gao W, Ferguson G, Connell P, Walshe T, O’Brien C, Redmond EM, Cahill PA.
- 2014
- Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression.
- Diab Vasc Dis Res. 2014 May 22;11(4):270-280.
126
Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O’Brien C, McKnight AJ, Willoughby CE
- 2014
- Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.
- Genet Med. 2014 Sep 18.
127
McNally S, O’Brien CJ. Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
- 2014
- Metabolomics/Proteomics strategies used to identify biomarkers for exfoliation glaucoma.
- J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S51-4.
128
McElnea EM, Hughes E, McGoldrick A, McCann A, Quill B, Docherty N, Irnaten M, Farrell M, Clark AF, O’Brien CJ, Wallace DM.
- 2014
- Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells.
- BMC Ophthalmol. 2014 Dec 2;14:153.
129
Quill B, Irnaten M, Docherty NG, McElnea EM, Wallace DM, Clark AF, O’Brien CJ
- 2015
- ‘Calcium channel blockade reduces mechanical strain induced extracellular matrix gene response in lamina cribrosa cells’.
- Br J Ophthalmol. 2015 Mar 20. pii: bjophthalmol-2014-306093. doi: 10.1136/bjophthalmol-2014-306093. [Epub ahead of print]
130
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The function of matricellular proteins in the lamina cribrosa and trabecular meshwork in glaucoma.
- J Ocul Pharmacol Ther. 2015 Apr 7. [Epub ahead of print]
131
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR
- 2015
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2015 Apr 21. [Epub ahead of print]
132
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95.
133
Siah WF, Loughman J, O’Brien C.
- 2015
- Lower Macular Pigment Optical Density in Foveal-Involved Glaucoma.
- Ophthalmology. 2015 Oct;122(10):2029-37.
134
Quill B, Henry E, Simon E, O’Brien CJ.
- 2015
- Evaluation of the Effect of Hypercapnia on Vascular Function in Normal Tension Glaucoma.
- Biomed Res Int. 2015;2015:418159.
135
Wallace DM, O’Brien CJ. The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- 2016
- The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma.
- Exp Eye Res. 2016 Jan;142:102-9.
136
O’Brien C, Clark AF.
- 2016
- Introduction to EER Special Issue on ocular fibrosis.
- Exp Eye Res. 2016 Jan;142:1.
137
Murphy RM, Bakir B, O’Brien C, Wiggs JL, Pasquale LR.
- 2016
- Drug-induced Bilateral Secondary Angle-Closure Glaucoma: A Literature Synthesis.
- J Glaucoma. 2016 Feb;25(2):e99-e105.
138
Pokrovskaya O, O’Brien C.
- 2016
- What's in a Gene? Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient.
- Case Rep Ophthalmol. 2016 Jan 21;7(1):54-60. doi: 10.1159/000443697. eCollection 2016 Jan 21.
139
McDonnell F, Irnaten M, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.
- PLoS One. 2016 Apr 28;11(4):e0153354. doi: 10.1371/journal.pone.0153354. eCollection 2016 Apr 28.
140
Treacy MP, O’Neill EC, Murphy M, O’Toole L, Delaney Y, O’Brien C, Connell PP.
- 2016
- Opportunistic detection of glaucomatous optic discs within a diabetic retinopathy screening service.
- Eur J Ophthalmol. 2016 Jun 10;26(4):315-20. doi: 10.5301/ejo.5000722. Epub 2015 Dec 17.
141
Paula JS, O’Brien C, Stamer WD.
- 2016
- Life under pressure: The role of ocular cribriform cells in preventing glaucoma.
- Exp Eye Res. 2016 Oct;151:150-9. doi: 10.1016/j.exer.2016.08.014. Epub 2016 Aug 25. Review.
142
McDonnell FS, McNally SA, Clark AF, O’Brien CJ, Wallace DM.
- 2016
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells.
- J Glaucoma. 2016 Oct;25(10):e834-e842.
143
Murphy ML, Pokrovskaya O, Galligan M, O’Brien C.
- 2017
- Corneal hysteresis in patients with glaucoma-like optic discs, ocular hypertension and glaucoma.
- BMC Ophthalmol. 2017 Jan 10;17(1):1. doi: 10.1186/s12886-016-0396-9.
144
O’Callaghan J, Crosbie DE, Cassidy PS, Sherwood JM, Flügel-Koch C, Lütjen-Drecoll E, Humphries MM, Reina-Torres E, Wallace D, Kiang AS, Campbell M, Daniel SW, Overby DR, O’Brien C, Tam LC, Humphries P.
- 2017
- Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.
- Hum Mol Genet. 2017 Feb 1. doi: 10.1093/hmg/ddx028.
145
Wallace DM, Pokrovskaya O, O’Brien CJ.
- 2015
- The Function of Matricellular Proteins in the Lamina Cribrosa and Trabecular Meshwork in Glaucoma.
- J Ocul Pharmacol Ther. 2015 Sep;31(7):386-95. doi: 10.1089/jop.2014.0163. Epub 2015 Apr 7. Review.
146
Barrett C, O’Brien C, Butler JS, Loughman J.
- 2017
- Barriers to glaucoma case finding as perceived by optometrists in Ireland.
- Clin Exp Optom. 2017 Jul 17. doi: 10.1111/cxo.12573.
147
Liu B, McNally S, Kilpatrick JI, Jarvis SP, O’Brien CJ.
- 2017
- Aging and ocular tissue stiffness in glaucoma.
- Surv Ophthalmol. 2017 Jun 27. pii: S0039-6257(15)30018-7. doi: 10.1016/j.survophthal.2017.06.007
148
Kamel K, Farrell M, O’Brien C.
- 2017
- Mitochondrial dysfunction in ocular disease: Focus on glaucoma.
- Mitochondrion. 2017 Jul;35:44-53. doi: 10.1016/j.mito.2017.05.004. Epub 2017 May 9.
149
Siah WF, O’Brien C, Loughman JJ.
- 2017
- Macular pigment is associated with glare-affected visual function and central visual field loss in glaucoma.
- Br J Ophthalmol. 2017 Oct 5. pii: bjophthalmol-2017-310215. doi: 10.1136/bjophthalmol-2017-310215. [Epub ahead of print]
150
Liu B, Kilpatrick JI, Lukasz B, Jarvis SP, McDonnell F, Wallace DM, Clark AF, O’Brien CJ.
- 2018
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814. doi: 1
151
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O’Brien C.
- 2018
- Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):831-842. doi: 10.1167/iovs.17-22531.
152
Barrett C, O’Brien C, Loughman J.
- 2018
- Glaucoma referral refinement in Ireland: managing the sensitivity-specificity paradox in optometric practice.
- Ophthalmic Physiol Opt. 2018 Feb 28. doi: 10.1111/opo.12446
153
Kamel K, Falzan K, Dervan E, O’Brien C.
- 2018
- Difference in intraocular pressure measurements between non-contact tonometry and Goldman applanation tonometry
- Ir J Med Sci. 2018
154
Kamel K, Bourke L, O’Brien C.
- 2018
- Clinical and Laboratory Biomarkers for Pseudoexfoliation Syndrome.
- J Glaucoma. 2018 Jul;27 Suppl 1:S111-S113.
155
Loskutova E, O’Brien C, Loskutov I, Loughman J.
- 2018
- Nutritional supplementation in the treatment of glaucoma: A systematic review.
- Surv Ophthalmol. 2018 Oct 6. pii: S0039-6257(18)30100-0.
156
Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, Kennedy C, Clerkin S, Doyle B, Godson C, Connell P, O’Brien C, Cagney G, Crean J.
- 2019
- Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.
- FASEB J. 2019 May;33(5):6667-6681. doi: 10.1096/fj.201800566RR
157
Bourke CM, Loughman J, Fltcroft DI, Loskutova E, O’Brien C.
- 2019
- We can't afford to turn a blind eye to myopia.
- QJM. 2019 Mar 26. pii: hcz076. doi: 10.1093/qjmed/hcz076.
158
Murtagh P, Greene G, O’Brien C.
- 2020
- Current application of machine learning in the screening and diagnosis of glaucoma: a systematic review and Meta-analysis.
- Int J Ophthalmic. 2020 Jan18;13(1):149-162
159
Greene AG, Eivers SB, Dervan EWJ,O’Brien CJ, Wallace DM.
- 2020
- Lysyl Oxidase Like 1: Biological roles and regulation.
- Exp Eye Res. 2020 Apr;193107975. doi:10.1016/j.exer.2020.107975. Epub 2020 Feb15.
160
Iraten M, O’Malley G, Clark AF, O’Brien CJ.
- 2020
- Transient receptor potential channels TRPC1/TRPC6 regulate lamina cribrosa cell extracellular matrix gene transcription and proliferation.
- Exp Eye Res. 2020 Apr;193:107980. doi: 10.1016/j.exer.2020.107980. Epub 2020 Feb 20.
161
Eivers SB, Greene AG, Dervan E, O’Brien C, Wallace D
- 2020
- Prevalence of Pseudoexfoliation Glaucoma Risk-associated Variants Within Lysyl Oxidase-like 1 in an Irish Population.
- J Glaucoma. 2020 Jun;29(6):417-422. doi:10.1097/IJG.0000000000001475.
162
Rahman N, O’Neill E, Irnaten M, Wallace D, O’Brien C.
- 2020
- Corneal Stiffness and Collagen Cross-Linking Proteins in Glaucoma: Potential for Novel Therapeutic Strategy.
- J Ocul Pharmacol Ther. 2020 Jul 13. doi: 10.1089/jop.2019.0118.
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Hopkins AA, Murphy R, Irnaten M, Wallace DM, Quill B, O’Brien C.
- 2020
- The Role of Lamina Cribrosa Tissue Stiffness and Fibrosis as Fundamental Biomechanical Drivers of Pathological Glaucomatous Cupping.
- Am J Physiol Cell Physiol. 2020 Jul 15. doi: 10.1152/ajpcell.00054.2020.
164
Kamel K, O’Brien CJ, Zhdanov AV, Papkovsky DB, Clark AF, Stamer WD, Irnaten M.
- 2020
- Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.
- Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):4. doi: 10.1167/iovs.61.13.4.
165
Irnaten M, Duff A, Clark A, O’Brien C.
- 2020
- Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.
- J Clin Med. 2020 Dec 26;10(1):62. doi: 10.3390/jcm10010062.
166
Greene AG, Eivers SB, McDonnell F, Dervan EWJ, O’Brien CJ, Wallace DM.
- 2020
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation.
- Exp Eye Res. 2020 Dec;201:108349. doi: 10.1016/j.exer.2020.108349. Epub 2020
167
Cassidy PS, Kelly RA, Reina-Torres E, Sherwood JM, Humphries MM, Kiang AS, Farrar GJ, O’Brien C, Campbell M, Stamer WD, Overby DR, Humphries P, O’Callaghan J.
- 2020
- siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.
- Mol Ther Methods Clin Dev. 2020 Oct 31;20:86-94. doi: 10.1016/j.omtm.2020.10.022. eCollection 2021 Mar 12.
168
Kamel K, Dervan E, Falzon K, O’Brien C.
- 2020
- Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals.
- Ir J Med Sci. 2019 Feb;188(1):321-325. doi: 10.1007/s11845-018-1795-0. Epub 2018 Apr 4.
169
Doolan E, O’Brien C.
- 2021
- Abnormal corneal properties in osteogenesis imperfect and glaucoma: a case series.
- BMJ Open Ophthalmic. 2021 Apr15;6(1):e000684 doi: 10.1136/bmjophth-2020-000684. eCollection 2021.
170
O’Regan A, O’Brien CJ, Eivers SB.
- 2021
- The lysophosphatidic acid axis in fibrosis: Implications for glaucoma.
- Wound Repair Regen. 2021 Jul;29(4):613-626. doi: 10.1111/wrr.12929. Epub 2021 May 19.
171
Hurley DJ, Iranaten, O’Brien C.
- 2021
- Metformin and Glaucoma-Review of Anti-Fibrotic Processes and Bioenergetics.
- Cells 2021 Aug 19;10(8):2131. Doi: 10.3390/cells10082131.
172
Kelly RA, Perkumas KM, Campbell M, Farrar GJ, Stamer WD, Humphries P, O’Callaghan J, O’Brien CJ.
- 2021
- Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma.
- Int J Mol Sci. 2021 Aug 31;22(17):9446. Doi 10.3390/ijms22179446.
173
Murphy R, Irnaten M, Hopkins A, O Callaghan J, Stamer WD, Clark AF, Wallace D, O’Brien CJ.
- 2022
- Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribosa Cells in Glaucoma.
- Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):16 doi: 10.1167/iovs.63.1.16.
174
Powell S, Doolan E, Curtin K, Doyle A, O’Brien C.
- 2022
- Audit of outcomes following attendance at the City West drive-through IOP glaucoma clinic during COVID-19 pandemic.
- Ir J Med Sci. 2022 Jan 16:1-10. doi: 10.1007/s11845-021-02893-9.
175
Powell S, Irnaten M, O’Brien C.
- 2022
- Glaucoma – A Stiff Eye in a Stiff Body
- Curr Eye Res. 2022 Mar 7:1-9. doi: 10.1080/02713683.2022.2039204.
176
Hurley DJ, Normile C, Irnaten M, O’Brien C.
- 2022
- The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma.
- Antioxidants (Basel). 2022 Apr 29;11(5):886. doi: 10.3390/antiox11050886
177
Murtagh P, O’Brien C.
- 2022
- Corneal Hysteresis, Intraocular Pressure and Progression of Glaucoma: Time for a “Hyst-Oric” Change in Clinical Practice?
- J Clin Med. 2022 May 20;11(10):2895. doi: 10.3390/jcm11102895
178
P Murtagh, S Neary, C.J O’Brien
- 2022
- Screening for Glaucoma in Adults: Our Vision
- Ir MedJ 2022 Sept 15; 115(8):646
179
Symth A, Callaghan B, Willoughby CE, C.J O’Brien
- 2022
- The Role of miR-29 Family in TGF-β Driven Fibrosis in Glaucomatous Optic Neuropathy
- Int J Mol Sci. 2022 Sep 6:23(18):10216. doi:10.3390/ijms
180
Imaten M, C.J.O’Brien
- 2023
- Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts.
- Int J Mol Sci. 2023 Jan 9;24(2):1287. doi 10.3390/jmis24021287