Showing 1 - 52 out of 52
52
  • Investigating the role of the protooncogene C-MET and the P13K/mTor signalling pathway in Lamina Cribrosa in Glaucoma.
  • UKEGS/IGA 2019 - 2020
  • C O’Brien, M Irnaten
51
  • Mechano-transduction and substrate stiffness of the Lamina Cribrosa.
  • Irish College of Ophthalmologists /Novartis Award. 2018
  • R Murphy, C O’Brien
50
  • Lamina cribrosa cell bioenergetics and metabolomics in glaucoma.
  • Royal College of Ophthalmologists/ International Glaucoma Association 2017-2018
  • C O’Brien, M Irnaten
49
  • Epigenetics in the Pathogenesis of pseudoexfoliation glaucoma.
  • Health Research Board 2017-19
  • D Wallace, C O’Brien
48
  • Role of Nox-4 in Lamina Cribrosa Fibrosis in Glaucoma.
  • Irish College of Ophthalmologists Award 2017
  • R Goetz, C O’Brien
47
  • To investigate the role of methylation in the regulation of Lysyloxidase Like I expression in Pseudoexfoliation glaucoma.
  • The Glaucoma Foundation 2015-16
  • D Wallace, C O’Brien
46
  • Mitochondrial Respiratory function in lamina cribrosa cells.
  • Irish College of Ophthalmology /Novartis Award. 2016
  • K Kamel /C O'Brien
45
  • Caveolins, Calcium Signalling and Fibrosis of Lamina Cribrosa Cells in Glaucoma.
  • Glaucoma Research Foundation, San Francisco Awards for Innovative Research
  • C O’Brien, D Wallace
44
  • An analysis of normal and glaucomatous human lamina cribrosa and trabecular meshwork cell behavious as determined by rigidity of surrounding extracellular matrix 2013-14
  • International Glaucoma Association /UK & Eire Glaucoma Society 2013-14
  • C O’Brien, D Wallace
43
  • Glaucoma: An Insight into Epigenomic Reprogramming
  • Health Research Board 2012-15
  • D Wallace, C O’Brien
42
  • Novel anti-connective tissue growth factor antibody therapy in pseudoexfoliation glaucoma.
  • Health Research Board 2011-13
  • C O’Brien, D Wallace, J Crean
41
  • Characterisation of several proteins identified in the serum of patients with Pseudoexfoliation glaucoma.
  • Pfizer Ireland /Irish College of Ophthmology 2010
  • F. Doyle, D. Wallace, C. O’Brien.
40
  • The relationship between oxidative stress and calcium homeostasis in human lamina cribrosa cells and their effects on extracellular matrix remodeling.
  • Pfizer Ireland /Irish College of Ophthmology 2010
  • W.F. Siah, D. Wallace, C.O’Brien.
39
  • Role of anti-GTGF antibody in Glaucoma.
  • International Glaucoma Association /UK & Eire Glaucoma Society 2009
  • D. Wallace, C. O’Brien.
38
  • Evaluation of pseudoexfoliation glaucoma associated auto-antigens as disease biomarkers and the role of their antigenic targets in neurodegeration.
  • Glaucoma Research Foundation, New York 2007-8
  • D Murphy, C O’Brien
37
  • Modulation of lamina cribrosa matrix remodeling in glaucoma.
  • National Glaucoma Research (American Health Assistance Foundation) 2007-9
  • C O’Brien, T Holmes, W Watson.
36
  • Mechanisms in diabetic retinopathy.
  • National Council for the Blind of Ireland 2005-7
  • C O’Brien, N Sweeney, L Cryan
35
  • Optic nerve gene expression studies.
  • Alcon Research Labs 2004
  • C O’Brien, R Kirwan
34
  • Molecular mechanism of retinal pericyte apoptosis in diabetic retinopathy.
  • Health Research Board, North-South Grants 2004-6
  • C O’Brien, A Stitt, T Cotter
33
  • Effect of TFG beta on matrix remodelling in glaucoma.
  • Mater College 2003
  • R Kirwan
32
  • Effects of hyperglycaemia on vascular endothelial function.
  • Phil Vizzard Research Fellowship 2002
  • P Connell, P Cahill, C O’Brien
31
  • The role of nitric oxide in retinal ganglion cell apoptosis. Implications for glaucoma.
  • Health Research Board 2002 -4
  • C O’Brien, T Cotter
30
  • Effect of pulsatatile flow in retinal microvascular cells
  • National Glaucoma Research 2002-2005
  • C O’Brien, P Cahill, T Walsh
29
  • Lamina Cribrosa fibroblasts in glaucoma
  • Alcon Research Labs 2002
  • C O’Brien, R Kirwan
28
  • Vascular endothelial function in diabetic retinopathy.
  • Irish College of Ophthalmology /Pharmacia 2001
  • P Connell, P Cahill, C O’Brien
27
  • An assessment of quality of life in people of 65 years and older who are registered as visually impaired in Ireland.
  • Health Research Board 2001
  • Gallagher, J Jackson, C O’Brien
26
  • To study nitric oxide independent vascular relaxation in human posterior ciliary arteries.
  • Royal College of Surgeons of Edinburgh 2000
  • C. O’Brien, P. McLoughlin
25
  • To evaluate the role of cyclic stretch on cultured trabecular meshwork cells in glaucoma.
  • International Glaucoma Association 2000
  • C. O’Brien, H. Devlin
24
  • To investigate cyclooxygenase activity in glaucoma.
  • International Glaucoma Association 2000
  • C. O’Brien, D. Fitzgerald
23
  • To study corticosteroid metabolism in glaucoma patients.
  • Royal College of Surgeons of Edinburgh 1999
  • C O’Brien
22
  • To study glare disability in glaucoma.
  • Allergan Pharmaceuticals 1999
  • C. O’Brien, P. Aspinall
21
  • Glare and its practice consequences in glaucoma.
  • Engineering and Physical Science Research Council, London 1998
  • P. Aspinall, C. O’Brien
20
  • Study the effects of glucocorticoids on cultured trabecular meshwork cells.
  • Royal College of Surgeons of Edinburgh 1998
  • C. O’Brien, R. Best, J. Seckl
19
  • To study ocular and systemic corticosteroid.
  • The Ross Foundation 1997
  • C. O’Brien, R Best, J. Seckl
18
  • To examine corticosteroid metabolism in glaucoma.
  • Sir Stanley and Lady Davidson Award 1997
  • R. Best, J. Seckl, C.O’Brien
17
  • To purchase a microscope for myography studies of isolated ocular blood vessels.
  • Sir Stanley and Lady Davidson Award 1997
  • C. Buckley, C. O’Brien
16
  • Corticosteroid metabolism in glaucoma.
  • Royal College of Surgeons of Edinburgh 1997
  • C. O’Brien, R Best, J. Seckl
15
  • To measure corticosteroid responsiveness in glaucoma
  • British Council for the Prevention of Blindness 1997
  • R Best, J Seckl, C O’Brien
14
  • To study vascular endothelial cell dysfunction and ocular vaso-reactivity in low tension glaucoma.
  • Royal National Institute for the Blind 1996
  • C. O’Brien, DJ Webb, P Hadoke
13
  • To investigate the in-vitro contractile responses of isolated orbital and ocular blood vessels.
  • Royal College of Surgeons of Edinburgh 1995
  • C O’Brien, P Hadoke
12
  • To study ocular blood flow in ocular hypertension.
  • International Glaucoma Association 1995
  • C O’Brien
11
  • To purchase a laser Doppler flowmeter to study retinal blood flow in glaucoma.
  • Ross Foundation 1994
  • C O’Brien
10
  • To purchase a pulsatile ocular blood flow machine.
  • International Glaucoma Association 1994
  • C O’Brien
09
  • To support community based shared-care of ocular hypertension and glaucoma with local optometrists.
  • Scottish Office Primary Care Fund 1994
  • C O’Brien, D Cameron
08
  • To fund a post-doctoral research fellow to study early visual dysfunction in glaucoma.
  • Royal National Institute for the Blind 1994
  • R Anderson, C O’Brien
07
  • Purchase of equipment to study psychophysical visual loss in glaucoma.
  • Ross Foundation 1993
  • C O’Brien
06
  • To purchase a confocal laser scanning ophthalmoscope for glaucoma research.
  • Alcon laboratories UK 1993
  • C O’Brien
05
  • To study ocular blood flow in low tension glaucoma .
  • The Guide Dogs for the Blind Association 1993
  • Z Butt, C O’Brien
04
  • To support research salaries.
  • Ciba Vision 1993 to support research salaries
  • C O’Brien
03
  • To support a research fellow for clinical studies with the flicker perimeter.
  • International Glaucoma Association/College of Ophthalmology Research Grant 1992
  • C O’Brien
02
  • Glaucoma Group Award 1991.
  • Glaucoma Group Award 1991.
  • C O’Brien
01
  • To design an automated flicker perimeter to study early visual field loss in glaucoma.
  • Mersey Regional Health Authority 1990
  • C O’Brien, A Ansons, P Hammond